| Long name: |
SLC29A4 Primary Polyclonal Antibody |
| Also known as: |
SLC29A4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SLC29A4 |
| Specificity: |
This is a highly specific antibody against SLC29A4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
440-490/530 |
| Subcellular location: |
Helical |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SLC29A4 |
| Gene ID number: |
222962 |
| Swiss Prot: |
Q7RTT9 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Does not seem to transport nucleoside and nucleoside analogs such as uridine, Glu-206 is essential for the cation selectivity and may function as the charge sensor for cationic substrates, In (PubMed:16873718) adenosine is efficiently transported but in a fashion highly sensitive to extracellular pH, May be involved in luminal transport of organic cations in the kidney and seems to use luminal proton gradient to drive organic cation reabsorption, May play a role in regulating central nervous system homeostasis of monoamine neurotransmitters, May play a role in the regulation of extracellular adenosine concentrations in cardiac tissues, Transport is chloride and sodium-independent but appears to be sensitive to changes in membrane potential, Weakly inhibited by the classical inhibitors of equilibrative nucleoside transport, adenosine, and azidothymidine, and nitrobenzylthioinosine, cytidine, dilazep, dipyridamole, dopamine, efficiently transporting many organic cations such as monoamine neurotransmitters 1-methyl-4-phenylpyridinium and biogenic amines including serotonin, guanosine, in particular during ischemia, inosine, norepinephrine and epinephrine, thymidine, with maximal activity in the pH range 5, 5, 5 to 6, Functions as a polyspecific organic cation transporter |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Equilibrative nucleoside transporter 4, PMAT, PSEC0113, Plasma membrane monoamine transporter, SLC29A4, Solute carrier family 29 member 4, hENT4, ENT4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SLC29A4 |
| Short name: |
SLC29A4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SLC29A4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23097 |
| Gene: |
SLC29A4 |
More about : SLC29A4 |
| Long gene name: |
solute carrier family 29 member 4 |
| Synonyms gene name: |
member 4 , member 4 solute carrier family 29 (equilibrative nucleoside transporter), solute carrier family 29 (nucleoside transporters) |
| Synonyms: |
FLJ34923 ENT4 |
| Locus: |
7p22, 1 |
| Discovery year: |
2003-10-08 |
| GenBank acession: |
AK075422 |
| Entrez gene record: |
222962 |
| Pubmed identfication: |
12838422 |
| RefSeq identity: |
NM_153247 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000023797 |