| Long name: |
TRIM25 Primary Polyclonal Antibody |
| Also known as: |
TRIM25 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TRIM25 |
| Specificity: |
This is a highly specific antibody against TRIM25 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
550-600/630 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRIM25 |
| Gene ID number: |
7706 |
| Swiss Prot: |
Q14258 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Involved in innate immune defense against viruses by mediating ubiquitination of DDX58, Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection, Mediates estrogen action in various target organs, Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway, Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
E3 ubiquitin/ISG15 ligase TRIM25, Estrogen-responsive finger protein, RING finger protein 147, RNF147, TRIM25, Tripartite motif-containing protein 25, Ubiquitin/ISG15-conjugating enzyme TRIM25, Z147, ZNF147, Zinc finger protein 147, EFP |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TRIM25 |
| Short name: |
TRIM25 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRIM25 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12932 |
| Gene: |
TRIM25 |
More about : TRIM25 |
| Long gene name: |
tripartite motif containing 25 |
| Synonyms gene: |
ZNF147 |
| Synonyms gene name: |
zinc finger protein 147 (estrogen-responsive finger protein) tripartite motif-containing 25 |
| Synonyms: |
EFP RNF147 |
| Locus: |
17q23, 1 |
| Discovery year: |
1994-03-16 |
| GenBank acession: |
D21205 |
| Entrez gene record: |
7706 |
| Pubmed identfication: |
7789997 |
| RefSeq identity: |
NM_005082 |
| Classification: |
Tripartite motif containing Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000178124 |