| Long name: |
FITC Conjugated, PKMYT1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PKMYT1 |
| Specificity: |
This is a highly specific antibody against PKMYT1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human PKMYT1 |
| Gene ID number: |
9088 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It may be a downstream target of Notch signaling pathway during eye development, It may be involved in phosphorylation of cdc2 on 'Tyr-15' to a lesser degree, It mediates phosphorylation of cdc2 predominantly on 'Thr-14' and is also involved in Golgi fragmentation, It preferentially phosphorylates and inactivates cell division cycle 2 protein (cdc2), PKMYT1 is negatively regulated by hyperphosphorylation during mitosis, and thus acts as a negative regulator of entry into mitosis (G2 to M transition), however tyrosine kinase activity is unclear and may be indirect, PKMYT1 is a member of the serine/threonine protein kinase family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MYT1 PPP1R126 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PKMYT1 Conjugated |
| Short name: |
FITC Conjugated, PKMYT1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, PKMYT1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29650 |
| Gene: |
PKMYT1 |
More about : PKMYT1 |
| Long gene name: |
membrane associated tyrosine/threonine 1 , protein kinase |
| Synonyms name: |
membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase protein phosphatase 1, regulatory subunit 126 |
| Locus: |
16p13, 3 |
| Discovery year: |
2005-01-20 |
| GenBank acession: |
AK097642 |
| Entrez gene record: |
9088 |
| Pubmed identfication: |
9001210 12606722 |
| RefSeq identity: |
NM_004203 |
| Classification: |
Protein phosphatase 1 regulatory subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000128975 |