| Long name: |
MST1R Primary Polyclonal Antibody |
| Also known as: |
MST1R PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MST1R |
| Specificity: |
This is a highly specific antibody against MST1R |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MST1R/Ron |
| Gene ID number: |
4486 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
ESTs have been isolated from several tissue libraries, In knockout studies, Ligand binding results in tyrosine phosphorylation of the beta chain, MST1R/RON (-/-) mice failed to survive past the periimplantation period, Ron expression has been documented in many normal human tissues, The MST1R/RON gene has been mapped to 3p21, The protein is a membrane-spanning, a HGF Receptor/MET-type protein kinase, a multifunctional cytokine that regulates cell adhesion, a region of frequent deletion or mutation in small cell lung and renal carcinoma, and has been implicated in the progression of several epithelial cancers, and survival, and testis and cancerous colon, and uterus, disulfide-linked heterodimer, growth, including normal colon, mediates the biological activities of macrophage-stimulating protein (MSP), motility, mouth, prostate, prostate, stomach, which results from cleavage of a glycosylated precursor into 35-kD (alpha) and 150-kD (beta) subunits, MST1R/Ron |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD136, CD136 antigen, CDw136, MACROPHAGE STIMULATING PROTEIN RECEPTOR, MSP receptor, MST1R variant RON30, MST1R variant RON62, Macrophage stimulating 1 receptor, Macrophage stimulating 1 receptor c met related tyrosine kinase, Macrophage stimulating protein receptor alpha chain, Macrophage stimulating protein receptor beta chain, Macrophage-Stimulating 1 Receptor MST1R, Macrophage-stimulating protein receptor beta chain, Mst1r, PTK 8, PTK8 protein tyrosine kinase 8, Protein-tyrosine kinase 8, RON, RON protein tyrosine kinase, RON variant E2E3, RON_HUMAN, Recepteur dâ, Soluble RON variant 1, Soluble RON variant 2, Soluble RON variant 3, Soluble RON variant 4, Stem cell derived tyrosine kinase, p185 RON, p185-Ron, ptk8, &euro, &trade, c met related tyrosine kinase, origine nantais RON |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MST1R |
| Short name: |
MST1R Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD136 and CDw136 and PTK8 and RON, MST1R and IDBG-35720 and ENSG00000164078 and 4486, MST1R and IDBG-645881 and ENSBTAG00000015046 and 525504, Mst1r and IDBG-198503 and ENSMUSG00000032584 and 19882, Plasma membranes, this GO :0001725 and stress fiber and cellular component this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004872 and receptor activity and molecular function this GO :0005011 and macrophage colony-stimulating factor receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006928 and cellular component movement and biological process this GO :0006952 and defense response and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007338 and single fertilization and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009615 and response to virus and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004714 : transmembrane receptor protein tyrosine kinase activity and also this GO :0004872 : receptor activity and also this GO :0005011 : macrophage colony-stimulating factor receptor activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004714 : transmembrane receptor protein tyrosine kinase activity, this GO :0004872 : receptor activity, this GO :0005011 : macrophage colony-stimulating factor receptor activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019899 : enzyme binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019899 : enzyme binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019899 and enzyme binding and molecular function this GO :0038145 and macrophage colony-stimulating factor signaling pathway and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) |
| Identity: |
7381 |
| Gene: |
MST1R |
More about : MST1R |
| Long gene name: |
macrophage stimulating 1 receptor |
| Synonyms gene: |
RON PTK8 |
| Synonyms gene name: |
PTK8 protein tyrosine kinase 8 |
| Synonyms: |
CDw136 CD136 |
| Synonyms name: |
c-met-related tyrosine kinase |
| Locus: |
3p21, 31 |
| Discovery year: |
1993-12-15 |
| GenBank acession: |
X70040 |
| Entrez gene record: |
4486 |
| Pubmed identfication: |
8386824 |
| Classification: |
CD molecules Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000156709 |