| Catalog number: | bs-4124R-A555 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | MEK5 Antibody, ALEXA FLUOR 555 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, MEK5 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-MEK5 PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | MEK5 |
| Specificity: | This is a highly specific antibody against MEK5 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 380-430/448 |
| Subcellular location: | Nucleus, Cytoplasm |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MEK5 |
| Gene ID Number: | 4217 |
| Swiss Prot: | Q99683 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Both p38 MAPK and JNKs control the transcription factors activator protein-1 (AP-1), MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7, MAP3K5/ASK1 is required for the innate immune response, Mediates signal transduction of various stressors like oxidative stress as well as by receptor-mediated inflammatory signals, Mediates signaling for determination of cell fate such as differentiation and survival, Once activated, Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation, Plays an important role in the cascades of cellular responses evoked by changes in the environment, These MAP2Ks in turn activate p38 MAPKs and c-jun N-terminal kinases (JNKs), acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K4/SEK1, such as the tumor necrosis factor (TNF) or lipopolysaccharide (LPS), which is essential for host defense against a wide range of pathogens, Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Synonyms: | MEK5 MAPKK5 HsT17454 |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | MEK5 |
| Short name: | MEK5 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, MEK5 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 6845 |
| Gene: | MAP2K5 | More about : MAP2K5 |
| Long gene name: | mitogen-activated protein kinase kinase 5 |
| Synonyms gene: | PRKMK5 |
| Locus: | 15q23 |
| Discovery year: | 1997-11-11 |
| GenBank acession: | U25265 |
| Entrez gene record: | 5607 |
| Pubmed identfication: | 7759517 |
| RefSeq identity: | NM_145162 |
| Classification: | Mitogen-activated protein kinase kinases |
| Havana BLAST/BLAT: | OTTHUMG00000133264 |
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