| Long name: |
DLP1 Primary Polyclonal Antibody |
| Also known as: |
DLP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DLP1 |
| Specificity: |
This is a highly specific antibody against DLP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
50-100/736 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DNM1L |
| Gene ID number: |
10059 |
| Swiss Prot: |
O00429 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also required for mitochondrial fission during mitosis, Facilitates developmentally regulated apoptosis during neural tube formation, Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed, Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism, Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, Required for a normal rate of cytochrome c release and caspase activation during apoptosis, Required for formation of endocytic vesicles, Required for normal brain development, Required for programmed necrosis execution, Through its function in mitochondrial division, by suppressing oxidative damage, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, including that of cerebellum, the function may require its recruitment by MFF to clathrin-containing vesicles, this requirement may depend upon the cell type and the physiological apoptotic cues, Functions in mitochondrial and peroxisomal division |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DLP1, DNM1L, DRP1, DVLP, Dnm1p/Vps1p-like protein, Dymple, Dynamin family member proline-rich carboxyl-terminal domain less, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, Dynamin-related protein 1, HdynIV, Dynamin-1-like protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DLP1 |
| Short name: |
DLP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
DLP1 (Antibody to) |
| Alternative technique: |
antibodies |