| Long name: |
FITC Conjugated, CASC3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CASC3 |
| Specificity: |
This is a highly specific antibody against CASC3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CASC3/MLN51 |
| Gene ID number: |
22794 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes, In mammalian cells, Its fly homolog, MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer, Magoh and Y14, The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, The function of MLN51 in mammals remains elusive, and translation, are core components of the exon junction complex (EJC), as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte, named barentsz, nonsense-mediated mRNA decay, the human homologs of mago nashi and tsunagi, this complex serves as a key modulator of spliced mRNA metabolism, &euro, &ldquo, The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exonâ, exon junctions as a consequence of pre-mRNA splicing |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
MLN51 BTZ |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CASC3 Conjugated |
| Short name: |
FITC Conjugated, CASC3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CASC3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17040 |
| Gene: |
CASC3 |
More about : CASC3 |
| Long gene name: |
cancer susceptibility 3 |
| Synonyms gene name: |
cancer susceptibility candidate 3 |
| Locus: |
17q21, 1 |
| Discovery year: |
2004-02-11 |
| GenBank acession: |
X80199 |
| Entrez gene record: |
22794 |
| Pubmed identfication: |
7490069 18332872 |
| RefSeq identity: |
NM_007359 |
| Classification: |
Exon junction complex |
| Havana BLAST/BLAT: |
OTTHUMG00000133323 |