| Long name: |
CASC3 Primary Polyclonal Antibody |
| Also known as: |
CASC3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CASC3 |
| Specificity: |
This is a highly specific antibody against CASC3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CASC3/MLN51 |
| Gene ID number: |
22794 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Human MLN51 is an RNA-binding protein present in ribonucleo-protein complexes, In mammalian cells, Its fly homolog, MLN51 is a nucleocytoplasmic shuttling protein that is overexpressed in breast cancer, Magoh and Y14, The EJC is assembled on spliced mRNAs and plays important roles in post-splicing events including mRNA export, The function of MLN51 in mammals remains elusive, and translation, are core components of the exon junction complex (EJC), as well as the proteins mago nashi and tsunagi have been shown to be required for proper oskar mRNA localization to the posterior pole of the oocyte, named barentsz, nonsense-mediated mRNA decay, the human homologs of mago nashi and tsunagi, this complex serves as a key modulator of spliced mRNA metabolism, &euro, &ldquo, The multiprotein exon junction complex (EJC) is deposited on mRNAs upstream of exonâ, exon junctions as a consequence of pre-mRNA splicing |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Btz, CASC3_HUMAN, Cancer susceptibility candidate gene 3 protein, MLN 51 protein, MLN51, MLN51, Metastatic lymph node protein 51, Protein CASC3, Protein MLN 51, Protein barentsz, Barentsz protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CASC3 |
| Short name: |
CASC3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CASC3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17040 |
| Gene: |
CASC3 |
More about : CASC3 |
| Long gene name: |
cancer susceptibility 3 |
| Synonyms gene name: |
cancer susceptibility candidate 3 |
| Synonyms: |
MLN51 BTZ |
| Locus: |
17q21, 1 |
| Discovery year: |
2004-02-11 |
| GenBank acession: |
X80199 |
| Entrez gene record: |
22794 |
| Pubmed identfication: |
7490069 18332872 |
| RefSeq identity: |
NM_007359 |
| Classification: |
Exon junction complex |
| Havana BLAST/BLAT: |
OTTHUMG00000133323 |