| Long name: |
ALEXA FLUOR 594 Conjugated, DAG1 (Tyr892) Polyclonal Antibody |
| Also known as: |
Anti-DAG1 Tyr892 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DAG1 Tyr892 |
| Specificity: |
This is a highly specific antibody against DAG1 Tyr892 |
| Modification: |
Phosphorylation |
| Modification Site: |
Tyr892 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human DAG1 around the phosphorylation site of Tyr892 |
| Gene ID Number: |
1605 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Alternative splicing results in multiple transcript variants all encoding the same protein, Apr 2010], Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies, Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane, The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence, rendering muscle fibers more susceptible to necrosis, Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix, [provided by RefSeq |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
A3a 156DAG AGRNR DAG |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
DAG1 (Tyr892) |
| Short name: |
DAG1 (Tyr892) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, dystroglycan 1 (dystrophin-associated glycoprotein 1) (Tyr892) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
156DAG and A3a and AGRNR and DAG and MDDGC7 and MDDGC9, BT, DAG1 and IDBG-34876 and ENSG00000173402 and 1605, Dag1 and IDBG-199494 and ENSMUSG00000039952 and 13138, alpha-actinin binding, nuclei, this GO :0001618 and virus receptor activity and molecular function this GO :0002011 and morphogenesis of an epithelial sheet and biological process this GO :0002162 and dystroglycan binding and molecular function this GO :0003779 and actin binding and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006509 and membrane protein ectodomain proteolysis and biological process this GO :0006607 and NLS-bearing protein import into nucleus and biological process this GO :0007016 and cytoskeletal anchoring at plasma membrane and biological process this GO :0008307 and structural constituent of muscle and molecular function this GO :0009279 and cell outer membrane and cellular component this GO :0009615 and response to virus and biological process this GO :0014044 and Schwann cell development and biological process this GO :0015631 and tubulin binding and molecular function this GO :0016010 and dystrophin-associated glycoprotein complex and cellular component this GO :0016011 and dystroglycan complex and cellular component this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016340 and calcium-dependent cell-matrix adhesion and biological process this GO :0017166 and vinculin binding and molecular function this GO :0019048 and modulation by virus of host morphology or physiology and biological process this GO :0021682 and nerve maturation and biological process this GO :0022011 and myelination in peripheral nervous system and biological process this GO :0030027 and lamellipodium and cellular component this GO :0030175 and filopodium and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0032403 and protein complex binding and molecular function this GO :0033268 and node of Ranvier and cellular component this GO :0034453 and microtubule anchoring and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042383 and sarcolemma and cellular component this GO :0043034 and costamere and cellular component this GO :0043237 and laminin-1 binding and molecular function this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0045121 and membrane raft and cellular component this GO :0045211 and postsynaptic membrane and cellular component this GO :0051393 and alpha-actinin binding and molecular function this GO :0051898 and negative regulation of protein kinase B signaling and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process this GO :0060445 and branching involved in salivary gland morphogenesis and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070938 and contractile ring and cellular component this GO :0071679 and commissural neuron axon guidance and biological process this GO :0071711 and basement membrane organization and biological process, this GO :0001618 : virus receptor activity, this GO :0001618 : virus receptor activity and also this GO :0002162 : dystroglycan binding and also this GO :0003779 : actin binding and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0008307 : structural constituent of muscle and also this GO :0015631 : tubulin binding and also this GO :0017166 : vinculin binding and also this GO :0032403 : protein complex binding and also this GO :0042169 : SH2 domain binding and also this GO :0043237 : laminin-1 binding and also this GO :0051393 : alpha-actinin binding, this GO :0002162 : dystroglycan binding, this GO :0003779 : actin binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0008307 : structural constituent of muscle, this GO :0015631 : tubulin binding, this GO :0017166 : vinculin binding, this GO :0032403 : protein complex binding, this GO :0042169 : SH2 domain binding, this GO :0043237 : laminin-1 binding, this GO :0051393 : alpha-actinin binding, 88492 and IDBG-645991 and ENSBTAG00000011580 and 281439, dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| Identity: |
2666 |
| Gene: |
DAG1 |
More about : DAG1 |
| Long gene name: |
dystroglycan 1 |
| Synonyms gene name: |
dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| Synonyms name: |
alpha-dystroglycan dystrophin-associated glycoprotein-1 beta-dystroglycan |
| Locus: |
3p21, 31 |
| Discovery year: |
1997-07-22 |
| GenBank acession: |
L19711 |
| Entrez gene record: |
1605 |
| Pubmed identfication: |
7774920 1741056 |
| Havana BLAST/BLAT: |
OTTHUMG00000156869 |
| Locus Specific Databases: |
Leiden Muscular Dystrophy pages LRG_854 |