| Long name: |
FITC Conjugated, IRGM Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IRGM |
| Specificity: |
This is a highly specific antibody against IRGM |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human IRGM |
| Gene ID number: |
345611 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
IRGM deficient mice show defects with intracellular microbial killing, IRGM has been shown to be required for host defences against a broad range of intracellular pathogens, IRGM is primarily expressed in all cells derived from B-cell lineages, More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli, Specifically, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation, and is highly expressed in macrophages following IFN-gamma stimulation, belonging to the GTPase superfamily, phagosome maturation and autophagy, IRGM belongs to a family of interferon-gamma inducible GTPases |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
LRG47 LRG-47 IFI1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
IRGM Conjugated |
| Short name: |
FITC Conjugated, IRGM Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
M (Antibody to), fluorecein coupled, immunity-related GTPase family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
IFI47 and IDBG-645396 and ENSBTAG00000015727 and 521987, IRGM and IDBG-306231 and ENSG00000237693 and 345611, Ifi47 and IDBG-262893 and ENSMUSG00000078920 and 15953, M, Plasma membranes, acting on acid anhydrides, acting on acid anhydrides, acting on acid anhydrides and molecular function this GO :0030670 and pha this GO cytic vesicle membrane and cellular component this GO :0042995 and cell projection and cellular component this GO :0045087 and innate immune response and biological process, hydrolase activity, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000421 and autophagic vacuole membrane and cellular component this GO :0001891 and pha this GO cytic cup and cellular component this GO :0005525 and GTP binding and molecular function this GO :0006914 and autophagy and biological process this GO :0006954 and inflammatory response and biological process this GO :0016020 and membrane and cellular component this GO :0016817 and hydrolase activity, this GO :0005525 : GTP binding, this GO :0005525 : GTP binding and also this GO :0016817 : hydrolase activity, this GO :0016817 : hydrolase activity, immunity-related GTPase family |
| Identity: |
29597 |
| Gene: |
IRGM |
More about : IRGM |
| Long gene name: |
immunity related GTPase M |
| Synonyms gene: |
IRGM1 |
| Synonyms gene name: |
M1 , immunity-related GTPase family |
| Locus: |
5q33, 1 |
| Discovery year: |
2005-02-21 |
| GenBank acession: |
BC038539 |
| Entrez gene record: |
345611 |
| Pubmed identfication: |
7561525 14576437 |
| RefSeq identity: |
NM_001145805 |
| Havana BLAST/BLAT: |
OTTHUMG00000163647 |