| Long name: |
ALEXA FLUOR 350 Conjugated, IRGM Polyclonal Antibody |
| Also known as: |
Anti-IRGM PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IRGM |
| Specificity: |
This is a highly specific antibody against IRGM |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IRGM |
| Gene ID Number: |
345611 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
IRGM deficient mice show defects with intracellular microbial killing, IRGM has been shown to be required for host defences against a broad range of intracellular pathogens, IRGM is primarily expressed in all cells derived from B-cell lineages, More recently IRGM has been shown to inhibit baseline hematopoietic proliferation and is required for a normal hematopoietic stem cell response to chemical and infectious stimuli, Specifically, and are selectively induced by IFN-gamma or bacterial lipopolysaccharide (LPS) stimulation, and is highly expressed in macrophages following IFN-gamma stimulation, belonging to the GTPase superfamily, phagosome maturation and autophagy, IRGM belongs to a family of interferon-gamma inducible GTPases |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
LRG47 LRG-47 IFI1 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
IRGM |
| Short name: |
IRGM Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, M (Antibody to), immunity-related GTPase family |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
IFI47 and IDBG-645396 and ENSBTAG00000015727 and 521987, IRGM and IDBG-306231 and ENSG00000237693 and 345611, Ifi47 and IDBG-262893 and ENSMUSG00000078920 and 15953, M, Plasma membranes, acting on acid anhydrides, acting on acid anhydrides, acting on acid anhydrides and molecular function this GO :0030670 and pha this GO cytic vesicle membrane and cellular component this GO :0042995 and cell projection and cellular component this GO :0045087 and innate immune response and biological process, hydrolase activity, this GO :0000139 and this GO lgi membrane and cellular component this GO :0000421 and autophagic vacuole membrane and cellular component this GO :0001891 and pha this GO cytic cup and cellular component this GO :0005525 and GTP binding and molecular function this GO :0006914 and autophagy and biological process this GO :0006954 and inflammatory response and biological process this GO :0016020 and membrane and cellular component this GO :0016817 and hydrolase activity, this GO :0005525 : GTP binding, this GO :0005525 : GTP binding and also this GO :0016817 : hydrolase activity, this GO :0016817 : hydrolase activity, immunity-related GTPase family |
| Identity: |
29597 |
| Gene: |
IRGM |
More about : IRGM |
| Long gene name: |
immunity related GTPase M |
| Synonyms gene: |
IRGM1 |
| Synonyms gene name: |
M1 , immunity-related GTPase family |
| Locus: |
5q33, 1 |
| Discovery year: |
2005-02-21 |
| GenBank acession: |
BC038539 |
| Entrez gene record: |
345611 |
| Pubmed identfication: |
7561525 14576437 |
| RefSeq identity: |
NM_001145805 |
| Havana BLAST/BLAT: |
OTTHUMG00000163647 |