HER2 (Thr686) Antibody, FITC Conjugated

Catalog number:	bs-4004R-FITC Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	HER2 (Thr686) Antibody, FITC Conjugated
Quantity:	0.1ml
Related search:	antibody thr antibodies conjugated erbb cell homolog fluorescent crossreactivity

More details Need more?:

Long name:	FITC Conjugated, HER2 (Thr686) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Anti-FITC Antibody
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	HER2 Thr686
Specificity:	This phosphorylation site is homologous to that of Thr687 in Mouse and Thr688 in Rat, This is a highly specific antibody against HER2 Thr686
Modification:	Phosphorylation
Modification site:	Thr686
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	660-700/1255
Subcellular location:	Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human HER2 around the phosphorylation site of Thr686
Gene ID number:	2064
Swiss Prot:	P04626
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription, Essential component of a neuregulin-receptor complex, GP30 is a potential ligand for this receptor, Implicated in transcriptional activation of CDKN1A, In the nucleus is involved in transcriptional regulation, In turn, Involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth, Regulates outgrowth and stabilization of peripheral microtubules (MTs), This prevents the phosphorylation of APC and CLASP2, Upon ERBB2 activation, allowing its association with the cell membrane, although neuregulins do not interact with it alone, but that apparently needs a coreceptor for ligand binding, membrane-bound APC allows the localization of MACF1 to the cell membrane, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane, the function involves STAT3 and SRC, which is required for microtubule capture and stabilization, Protein tyrosine kinase that is part of several cell surface receptor complexes
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	494nm/518nm
Synonyms:	NEU HER-2 CD340 HER2
Properties:	Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	HER2 (Thr686) Conjugated
Short name:	FITC Conjugated, HER2 (Thr686) Antibody
Technique:	Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	FITC
Alternative name:	fluorecein coupled, HER2 (Thr686) (Antibody to)
Alternative technique:	antibodies
Identity:	3430
Gene:	ERBB2 | More about : ERBB2
Long gene name:	erb-b2 receptor tyrosine kinase 2
Synonyms gene:	NGL
Synonyms gene name:	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog) v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
Synonyms name:	neuro/glioblastoma derived oncogene homolog human epidermal growth factor receptor 2
Locus:	17q12
Discovery year:	2001-06-22
GenBank acession:	X03363
Entrez gene record:	2064
RefSeq identity:	NM_004448
Classification:	CD molecules Minor histocompatibility antigens Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT:	OTTHUMG00000179300
Locus Specific Databases:	LRG_724

• #antibody
• #thr
• #antibodies
• #conjugated
• #erbb
• #cell
• #homolog
• #fluorescent
• #crossreactivity