| Long name: |
HRP Conjugated, PRKAR1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
HRP Conjugated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PRKAR1 |
| Specificity: |
This is a highly specific antibody against PRKAR1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Protein Kinase A regulatory subunit I alpha |
| Gene ID number: |
5573 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A nonconventional nuclear localization sequence (NLS) has been found for this protein which suggests a role in DNA replication via the protein serving as a nuclear transport protein for the second subunit of the Replication Factor C (RFC40), Four different regulatory subunits and three catalytic subunits have been identified in humans, Jul 2008], Mutations in this gene cause Carney complex (CNC), The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits, This gene can fuse to the RET protooncogene by gene rearrangement and form the thyroid tumor-specific chimeric oncogene known as PTC2, This gene encodes one of the regulatory subunits, This protein was found to be a tissue-specific extinguisher that down-regulates the expression of seven liver genes in hepatoma x fibroblast hybrids, Three alternatively spliced transcript variants encoding the same protein have been observed, [provided by RefSeq, cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits, cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins, cAMP is a signaling molecule important for a variety of cellular functions |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CNC1 |
| Properties: |
Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase |
| Gene target: |
PRKAR1 Conjugated |
| Short name: |
Conjugated, PRKAR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
HRP |
| Alternative name: |
horseradish peroxidase coupled, PRKAR1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9388 |
| Gene: |
PRKAR1A |
More about : PRKAR1A |
| Long gene name: |
protein kinase cAMP-dependent type I regulatory subunit alpha |
| Synonyms gene: |
PRKAR1 TSE1 |
| Synonyms gene name: |
alpha protein kinase, cAMP-dependent, cAMP-dependent, regulatory, regulatory subunit type I alpha , tissue specific extinguisher 1 protein kinase, type I |
| Synonyms name: |
Carney complex type 1 |
| Locus: |
17q24, 2 |
| Discovery year: |
1988-05-11 |
| Entrez gene record: |
5573 |
| Pubmed identfication: |
3479018 10973256 |
| Havana BLAST/BLAT: |
OTTHUMG00000180128 |
| Locus Specific Databases: |
LRG_514 |