| Long name: |
MSH gamma Primary Polyclonal Antibody |
| Also known as: |
MSH gamma PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MSH gamma |
| Specificity: |
MSH gamma itself is too small to be detected by WB, This antibody will detect Pro-opiomelanocortin, and is then cleaved to produce MSH gamma, as well as MSH gamma, due to the fact that this protein is contained within this chain, This is a highly specific antibody against MSH gamma |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
77-87/267 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MSH gamma |
| Gene ID number: |
5443 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alternatively spliced transcript variants encoding the same protein have been described, In other tissues, Mutations in this gene have been associated with early onset obesity, The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, There are eight potential cleavage sites within the polypeptide precursor and, These include several distinct melanotropins, [provided by RefSeq], adrenal insufficiency, adrenocorticotrophin, all cleavage sites may be used, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides, and epithelium, and immune modulation, and lipotropin beta are the major end products, and red hair pigmentation, depending on tissue type and the available convertases, essential for normal steroidogenesis and the maintenance of normal adrenal weight, giving rise to peptides with roles in pain and energy homeostasis, including the hypothalamus, lipotropins, melanocyte stimulation, placenta, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions, tissue-specific, This gene encodes a polypeptide hormone precursor that undergoes extensive |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
COLI_HUMAN, Melanocyte Stimulating Hormone, Melanotropin gamma, POMC, Proopiomelanocortin, Gamma MSH |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MSH gamma |
| Short name: |
MSH gamma Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MSH g (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9201 |
| Gene: |
POMC |
More about : POMC |
| Long gene name: |
proopiomelanocortin |
| Synonyms: |
MSH POC CLIP ACTH NPP LPH |
| Synonyms name: |
adrenocorticotropin beta-lipotropin alpha-melanocyte stimulating hormone beta-melanocyte stimulating hormone beta-endorphin adrenocorticotropic hormone opiomelanocortin prepropeptide |
| Locus: |
2p23, 3 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
5443 |
| Pubmed identfication: |
6254047 9620771 |
| RefSeq identity: |
NM_001035256 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000094764 |