| Long name: |
Recombinant Human Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) |
| Alternative names: |
CARD-carrying kinase, CARD-containing IL-1 beta ICE-kinase, CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, RIP-2, RIP-2, RIP-like-interacting CLARP kinase, Receptor-interacting protein 2, Receptor-interacting serine/threonine-protein kinase 2, Tyrosine-protein kinase RIPK2 (EC:2, growth-inhibiting gene 30, receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase, receptor-interacting protein 2, receptor-interacting serine-threonine kinase 2, receptor-interacting serine/threonine-protein kinase 2, tyrosine-protein kinase RIPK2, 2), 7, 10, receptor-interacting serine/threonine-protein kinase 2 |
| Gene name: |
RIPK2 |
| Other gene names: |
CARD-containing IL-1 beta ICE-kinase, CARD3, CARDIAK, CARDIAK, CCK, GIG30, RICK, RICK, RIP-2, RIP2, RIP2, RIPK2, RIPK2 |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, coli, Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) is a recombinant protein expressed in E |
| Product category: |
Recombinant Proteins |
| Expression system: |
coli, E |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine,  , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Description: |
AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, It contains an &alpha, It is non-essential in humans, UCA, UCC, UCG, a carboxyl group, meaning the body can synthesize it, -amino group (which is in the protonated &minus, NH+ 3 form under biological conditions), Serine protease |
| Gene target: |
Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) |
| Short name: |
Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) |
| Species: |
Humans, Human |
| Alternative name: |
sapiens Receptor-interacting serine/threonine-protein phosphorylation catalyst 2 (receptor-interacting serine-threonine kinase 2), H |
| Alternative to gene target: |
CARD3 and CARDIAK and CCK and GIG30 and RICK and RIP2, Cytoplasm, RIPK2 and IDBG-27941 and ENSG00000104312 and 8767, RIPK2 and IDBG-645358 and ENSBTAG00000015271 and 534407, Ripk2 and IDBG-130745 and ENSMUSG00000041135 and 192656, leucine rich repeat containing receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043234 and protein complex and cellular component this GO :0043330 and response to exogenous dsRNA and biological process this GO :0045087 and innate immune response and biological process this GO :0045627 and positive regulation of T-helper 1 cell differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070423 and nucleotide-binding oli this GO merization domain containing signaling pathway and biological process this GO :0070427 and nucleotide-binding oli this GO merization domain containing 1 signaling pathway and biological process this GO :0070431 and nucleotide-binding oli this GO merization domain containing 2 signaling pathway and biological process this GO :0070555 and response to interleukin-1 and biological process this GO :0070671 and response to interleukin-12 and biological process this GO :0070673 and response to interleukin-18 and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process this GO :0071224 and cellular response to peptidoglycan and biological process this GO :0071225 and cellular response to muramyl dipeptide and biological process, this GO :0000187 and activation of MAPK activity and biological process this GO :0001961 and positive regulation of cytokine-mediated signaling pathway and biological process this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002250 and adaptive immune response and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0002827 and positive regulation of T-helper 1 type immune response and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005856 and cytoskeleton and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0007254 and JNK cascade and biological process this GO :0008152 and metabolic process and biological process this GO :0010800 and positive regulation of peptidyl-threonine phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0004871 : signal transducer activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0004871 : signal transducer activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0030274 : LIM domain binding, this GO :0042803 : protein homodimerization activity, this GO :0050700 : CARD domain binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0030274 : LIM domain binding and also this GO :0042803 : protein homodimerization activity and also this GO :0050700 : CARD domain binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030274 and LIM domain binding and molecular function this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0031982 and vesicle and cellular component this GO :0032722 and positive regulation of chemokine production and biological process this GO :0032727 and positive regulation of interferon-alpha production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0032729 and positive regulation of interferon-gamma production and biological process this GO :0032735 and positive regulation of interleukin-12 production and biological process this GO :0032743 and positive regulation of interleukin-2 production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0032874 and positive regulation of stress-activated MAPK cascade and biological process this GO :0033091 and positive regulation of immature T cell proliferation and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, receptor-interacting serine-threonine kinase 2 |
| Identity: |
10020 |
| Gene: |
RIPK2 |
More about : RIPK2 |
| Long gene name: |
receptor interacting serine/threonine kinase 2 |
| Synonyms gene name: |
receptor-interacting serine-threonine kinase 2 |
| Synonyms: |
RICK RIP2 CARDIAK CARD3 |
| Locus: |
8q21, 3 |
| Discovery year: |
1999-05-07 |
| GenBank acession: |
AC004003 |
| Entrez gene record: |
8767 |
| Pubmed identfication: |
9575181 9705938 |
| Classification: |
Caspase recruitment domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000163809 |