| Long name: |
FITC Conjugated, GPX4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
GPX4 |
| Specificity: |
This is a highly specific antibody against GPX4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Glutathione Peroxidase 4 |
| Gene ID number: |
2879 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
All mammalian GPx family members, Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation, GPx2, Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, There are several isoforms which differ in their primary structure and localization, also known as gastrointestinal GPx (GI-GPx), can reduce many hydroperoxides including hydroperoxides integrated in membranes, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, first of the GPx family to be discovered, hydroperoxy lipids in low density lipoprotein or thymine, is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract, possess selenocysteine at the active site, Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
PHGPx MCSP |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GPX4 Conjugated |
| Short name: |
FITC Conjugated, GPX4 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, GPX4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4556 |
| Gene: |
GPX4 |
More about : GPX4 |
| Long gene name: |
glutathione peroxidase 4 |
| Synonyms gene name: |
glutathione peroxidase 4 (phospholipid hydroperoxidase) |
| Synonyms name: |
phospholipid hydroperoxidase |
| Locus: |
19p13, 3 |
| Discovery year: |
1993-05-03 |
| GenBank acession: |
BC039849 X71973 |
| Entrez gene record: |
2879 |
| Pubmed identfication: |
8287691 8039723 10464096 |
| RefSeq identity: |
NM_002085 |
| Classification: |
Selenoproteins |
| Havana BLAST/BLAT: |
OTTHUMG00000181874 |