| Long name: |
FITC Conjugated, SMC1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SMC1 |
| Specificity: |
This is a highly specific antibody against SMC1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
150-200/1233 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human SMC1 |
| Gene ID number: |
8243 |
| Swiss Prot: |
Q14683 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
At anaphase, Central component of cohesin complex, Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped, The cohesin complex is required for the cohesion of sister chromatids after DNA replication, The cohesin complex may also play a role in spindle pole assembly during mitosis, Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint, allowing sister chromatids to segregate, or via its phosphorylation by ATR, the complex is cleaved and dissociates from chromatin, Involved in chromosome cohesion during cell cycle and in DNA repair |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CDLS2, DXS423E, KIAA0178, SB1, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1A, SMC1L1, SMC1alpha, SMCB, Structural maintenance of chromosomes protein 1A, 8, SMC1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SMC1 Conjugated |
| Short name: |
FITC Conjugated, SMC1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SMC1 (Antibody to) |
| Alternative technique: |
antibodies |