| Long name: |
RCC1 Primary Polyclonal Antibody |
| Also known as: |
RCC1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RCC1 |
| Specificity: |
This is a highly specific antibody against RCC1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
2-50/421 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RCC1 |
| Gene ID number: |
1104 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
RCC1, RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin, and, but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, to increase the affinity of chromatin for NE membranes, where bound, with chromatin , Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CHC 1, CHC1, Chromosome condensation 1, Chromosome condensation protein 1, Guanine nucleotide releasing protein, HERC2, RCC 1, RCC1 I, Ran GEF, RanGEF, Regulator of chromosome condensation, Regulator of chromosome condensation 1, SHEP1, Cell cycle regulatory protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RCC1 |
| Short name: |
RCC1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RCC1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1913 |
| Gene: |
RCC1 |
More about : RCC1 |
| Long gene name: |
regulator of chromosome condensation 1 |
| Synonyms gene: |
CHC1 |
| Synonyms gene name: |
chromosome condensation 1 |
| Locus: |
1p35, 3 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
X12654 |
| Entrez gene record: |
1104 |
| Pubmed identfication: |
7851910 |
| RefSeq identity: |
NM_001269 |
| Havana BLAST/BLAT: |
OTTHUMG00000003645 |