| Catalog number: | bs-3517R-A555 |
|---|---|
| Price: | 265 € |
| Supplier: | MBS Polyclonals |
| Product name: | PAK4 Antibody, ALEXA FLUOR 555 |
| Quantity: | 0.06 ml |
| Related search: |
| Long name: | ALEXA FLUOR 555 Conjugated, PAK4 Polyclonal Antibody |
|---|---|
| Also known as: | Anti-PAK4 PAb ALEXA FLUOR 555 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 555, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | PAK4 |
| Specificity: | This is a highly specific antibody against PAK4 |
| Modification: | Unmodified |
| Modification Site: | None |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Source: | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PAK4 |
| Gene ID Number: | 10298 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | All PAK family members are characterized by the presence of p21-binding domain, Current data strongly implicates PAK-4 in oncogenesis, PAK4 is frequently overexpressed in human tumor cell lines of various tissue origins, Phosphospecific directed against serine 474 detect activated PAK4 on the Golgi membrane when PAK4 is co-expressed with activated Cdc42, Serine (Ser-474) is the likely autophosphorylation site in the kinase domain of PAK4 in vivo, and lipids, and transcription, apoptosis, dynamics of the cytoskeleton, including the cell cycle, oncogenic transformation, p21-activated kinases are regulated by the small GTP-binding proteins Rac and Cdc42, which stimulate autophosphorylation and phosphorylation of exogenous substrates, p21-activated kinases (PAKs) belong to the family of serine/threonine kinases involved in the control of various cellular processes |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 553nm/568nm |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 555, Alexa Fluor |
| Gene target: | PAK4 |
| Short name: | PAK4 Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 555 |
| Alternative name: | ALEXA FLUOR 555, PAK4 (Antibody to) |
| Alternative technique: | antibodies |
| Identity: | 16059 |
| Gene: | PAK4 | More about : PAK4 |
| Long gene name: | p21 (RAC1) activated kinase 4 |
| Synonyms gene name: | p21(CDKN1A)-activated kinase 4 p21 protein (Cdc42/Rac)-activated kinase 4 |
| Locus: | 19q13, 2 |
| Discovery year: | 2001-07-12 |
| GenBank acession: | AJ011855 |
| Entrez gene record: | 10298 |
| Pubmed identfication: | 9822598 10461188 |
| Havana BLAST/BLAT: | OTTHUMG00000182800 |
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