| Long name: |
ALEXA FLUOR 647 Conjugated, ID2 Polyclonal Antibody |
| Also known as: |
Anti-ID2 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ID2 |
| Specificity: |
This is a highly specific antibody against ID2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
33-82/134 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GIG8/ID2 |
| Gene ID Number: |
3398 |
| Swiss Prot: |
Q02363 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Implicated in regulating a variety of cellular processes, Inhibits skeletal muscle and cardiac myocyte differentiation, Plays a role in both the input and output pathways of the circadian clock: in the input component, Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer, Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm, and neoplastic transformation, angiogenesis, apoptosis, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism, differentiation, including cellular growth, is involved in modulating the magnitude of photic entrainment and in the output component, senescence, Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
GIG8 bHLHb26 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ID2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ID2 |
| Short name: |
ID2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, dominant negative helix-loop-helix protein (Antibody to), inhibitor on Desoxyribonucleic acid binding 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046983 and protein dimerization activity and molecular function this GO :0048468 and cell development and biological process this GO :0048469 and cell maturation and biological process this GO :0048541 and Peyer's patch development and biological process this GO :0048557 and embryonic digestive tract morphogenesis and biological process this GO :0048661 and positive regulation of smooth muscle cell proliferation and biological process this GO :0048663 and neuron fate commitment and biological process this GO :0048711 and positive regulation of astrocyte differentiation and biological process this GO :0048715 and negative regulation of oli this GO dendrocyte differentiation and biological process this GO :0060612 and adipose tissue development and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0061030 and epithelial cell differentiation involved in mammary gland alveolus development and biological process this GO :0061031 and endodermal digestive tract morphogenesis and biological process this GO :0071158 and positive regulation of cell cycle arrest and biological process this GO :0071285 and cellular response to lithium ion and biological process this GO :0071931 and positive regulation of transcription involved in G1/S transition of mitotic cell cycle and biological process this GO :0090398 and cellular senescence and biological process this GO :2000045 and regulation of G1/S transition of mitotic cell cycle and biological process this GO :2000178 and negative regulation of neural precursor cell proliferation and biological process, ID2 and IDBG-27111 and ENSG00000115738 and 3398, ID2 and IDBG-638503 and ENSBTAG00000021187 and 505025, Id2 and IDBG-131550 and ENSMUSG00000020644 and 15902, bHLHb26 and GIG8 and ID2A and ID2H, dominant negative helix-loop-helix protein, nuclei, protein dimerization activity, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000785 and chromatin and cellular component this GO :0001656 and metanephros development and biological process this GO :0001779 and natural killer cell differentiation and biological process this GO :0002521 and leukocyte differentiation and biological process this GO :0003149 and membranous septum morphogenesis and biological process this GO :0003166 and bundle of His development and biological process this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0007275 and multicellular organismal development and biological process this GO :0007507 and heart development and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009649 and entrainment of circadian clock and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0014003 and oli this GO dendrocyte development and biological process this GO :0019216 and regulation of lipid metabolic process and biological process this GO :0021772 and olfactory bulb development and biological process this GO :0032922 and circadian regulation of gene expression and biological process this GO :0033598 and mammary gland epithelial cell proliferation and biological process this GO :0042752 and regulation of circadian rhythm and biological process this GO :0043153 and entrainment of circadian clock by photoperiod and biological process this GO :0043234 and protein complex and cellular component this GO :0043353 and enucleate erythrocyte differentiation and biological process this GO :0043392 and negative regulation of DNA binding and biological process this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0044325 and ion channel binding and molecular function this GO :0045475 and locomotor rhythm and biological process this GO :0045578 and negative regulation of B cell differentiation and biological process this GO :0045600 and positive regulation of fat cell differentiation and biological process this GO :0045648 and positive regulation of erythrocyte differentiation and biological process this GO :0045651 and positive regulation of macrophage differentiation and biological process this GO :0045665 and negative regulation of neuron differentiation and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045777 and positive regulation of blood pressure and biological process this GO :0045787 and positive regulation of cell cycle and biological process this GO :0045892 and negative regulation of transcription, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0044325 : ion channel binding and also this GO :0046983 : protein dimerization activity, this GO :0044325 : ion channel binding, this GO :0046983 : protein dimerization activity, inhibitor of DNA binding 2 |
| Identity: |
5361 |
| Gene: |
ID2 |
More about : ID2 |
| Long gene name: |
HLH protein , inhibitor of DNA binding 2 |
| Synonyms gene name: |
dominant negative helix-loop-helix protein , inhibitor of differentiation 2 inhibitor of DNA binding 2 |
| Synonyms name: |
cell growth-inhibiting gene 8 |
| Locus: |
2p25, 1 |
| Discovery year: |
1994-12-22 |
| Entrez gene record: |
3398 |
| Pubmed identfication: |
8294468 |
| RefSeq identity: |
NM_002166 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000112454 |