Rb/P105 RB (Thr821) Antibody, Biotin Conjugated

Catalog number:	bs-3452R-Biotin Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	Rb/P105 RB (Thr821) Antibody, Biotin Conjugated
Quantity:	0.1ml
Related search:	gene thr antibodies rbp protein nfkb short

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Long name:	Biotin Conjugated, Rb/P105 RB (Thr821) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	Biotinylated
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Rb/P105 RB Thr821
Specificity:	This is a highly specific antibody against Rb/P105 RB Thr821
Modification:	Phosphorylation
Modification site:	Thr821
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human Retinoblastoma associated protein around the phosphorylation site of Thr821
Gene ID number:	5925
Tested applications:	IHC-P, WB
Recommended dilutions:	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	ATF2, Aberrations in the Rb gene have been implicated in cancers of breast, Elf1 and cAbl, It forms a complex with SV40 large T antigen, PU1, Rb is phosphorylated on serine and threonine, Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth, This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks), UBF, adenovirus E1A, and human papilloma virus 16E, and leukemia, but not on tyrosine residues, colon, kidney, nasopharynx, prostate, Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms:	LYT-10 p52 p105 NF-kB2 p49/p100
Properties:	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	Rb/P105 RB (Thr821) Conjugated
Short name:	Conjugated, Rb/P105 RB (Thr821) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Biotin
Alternative name:	biotinilated coupled, Rb/P105 RB (Thr821) (Antibody to)
Alternative technique:	antibodies
Identity:	7795
Gene:	NFKB2 | More about : NFKB2
Long gene name:	nuclear factor kappa B subunit 2
Synonyms gene name:	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Locus:	10q24, 32
Discovery year:	1991-11-14
GenBank acession:	X61498
Entrez gene record:	4791
Pubmed identfication:	1876189
Classification:	Ankyrin repeat domain containing NF-kappa B complex subunits
Havana BLAST/BLAT:	OTTHUMG00000018962

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