Smad3 (Ser423 + Ser425) Antibody, Cy3 Conjugated

Catalog number:	bs-3425R-Cy3 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	Smad3 (Ser423 + Ser425) Antibody, Cy3 Conjugated
Quantity:	100ul
Related search:	ser smad antibody antibodies this homolog nanometer

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Long name:	Cy3 Conjugated, Smad3 (Ser423 + Ser425) Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	cy3 conjugation kit
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Smad3 Ser423 + Ser425
Specificity:	These phosphorylation sites are homologous across the species listed, This is a highly specific antibody against Smad3 Ser423 + Ser425
Modification:	Phosphorylation
Modification site:	Ser423 + Ser425
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	380-425/425
Subcellular location:	Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human Smad3 around the phosphorylation site of Ser423/425 [CS(p-S)V(p-S)]
Gene ID number:	4088
Swiss Prot:	P84022
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription, Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and by altering the TGF-mediated chemotaxis of monocytes, Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator, Regulator of chondrogenesis and osteogenesis and inhibits early healing of bone fractures, This effect on wound healing appears to be hormone-sensitive, activates transcription, on formation of the SMAD3/SMAD4 complex, Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	512, 550nm/570, 615nm
Synonyms:	HSPC193, HsT17436, JV15-2, LDS1C, MAD homolog 3, MADH3, Mad3, Mothers against DPP homolog 3, Mothers against decapentaplegic homolog 3, SMAD 3, SMAD family member 3, Smad3, hMAD-3, hSMAD3, LDS3
Properties:	1 of the Smad3 (Ser423 + Ser425) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	Smad3 (Ser423 + Ser425) Conjugated
Short name:	Conjugated, Smad3 (Ser423 + Ser425) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy3
Alternative name:	cyanine 3 coupled, SMAD family member 3 (Ser423 and Ser425) (Antibody to)
Alternative technique:	antibodies

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