| Long name: |
PDGF Receptor beta (Tyr740) Antibody |
| Also known as: |
PDGF Receptor beta (Tyr740) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PDGF Receptor beta Tyr740 |
| Specificity: |
This is a highly specific antibody against PDGF Receptor beta Tyr740 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr740 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PDGF Receptor beta around the phosphorylation site of Tyr740 [GG(p-Y)MD] |
| Gene ID number: |
5159 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A translocation between chromosomes 5 and 12, ETV6, The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, These growth factors are mitogens for cells of mesenchymal origin, This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, [provided by RefSeq], all three genes may be implicated in the 5-q syndrome, composed of both platelet-derived growth factor receptor alpha and beta polypeptides, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia, that fuses this gene to that of the translocation, This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Beta platelet derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD 140B, CD140 antigen-like family member B, CD140B, CD140B, CD140b antigen, JTK12, OTTHUMP00000160528, PDGF R beta, PDGF Receptor beta phospho Tyr740, PDGF Receptor beta phospho Y740, PDGF-R-beta, PDGFR, PDGFR 1, PDGFR beta, PDGFR1, PDGFRB, PGFRB_HUMAN, Platelet derived growth factor receptor 1, Platelet derived growth factor receptor beta, Platelet derived growth factor receptor beta, polypeptide, PDGFRBphospho Y740 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PDGF Receptor beta (Tyr740) |
| Short name: |
PDGF Receptor beta (Tyr740) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PDGF Receptor b (Tyr740) (Antibody to) |
| Alternative technique: |
antibodies |