| Long name: |
PAK2 (Ser20) Primary Polyclonal Antibody |
| Also known as: |
PAK2 (Ser20) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PAK2 Ser20 |
| Specificity: |
This is a highly specific antibody against PAK2 Ser20 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser20 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human PAK2 around the phosphorylation site of Ser20 |
| Gene ID number: |
5062 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), CDC42 and RAC1, PAK 2, The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, The three most common isoforms are PAK 1, These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, and PAK 3 (also known as alpha PAK, and beta PAK, and caspase mediated proteolytic cleavage, and have been implicated in a wide range of biological activities, and may play a role in regulating the apoptotic events in the dying cell, catalyzed by Cdc42, gamma PAK, interaction with Src homology 3 (SH3) domains, is required for activation of PAK, members of which are activated by small molecular weight GTPases, respectively), P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
65-KD antibody p21-activated protein kinase I, CB422, EC 2, Gamma PAK, Kinase, PAK 2, PAK2 phospho Ser20, PAK65, PAKgamma, S6 H4 kinase, Serine threonine protein kinase PAK 2, hPAK65, p-PAK2 S20, p-PAK2 Ser20, p21 CDKN1A-activated kinase 2a, p21 activated kinase 2, p21 protein Cdc42 Rac activated kinase 2, p21 protein Cdc42/Rac-activated kinase 2, p21-activated kinase, p21CDKN1A activated kinase 2, p58, p65PAK, 1, 7, 11, PAK2 phospho S20 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PAK2 (Ser20) |
| Short name: |
PAK2 (Ser20) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
p21 protein (Cdc42/Rac)-activated kinase 2 (Ser20) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PAK2 and IDBG-634020 and ENSBTAG00000047856 and 513673, PAK2 and IDBG-71333 and ENSG00000180370 and 5062, PAK65 and PAKgamma, Pak2 and IDBG-153570 and ENSMUSG00000022781 and 224105, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007015 and actin filament organization and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0016032 and viral process and biological process this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0019901 : protein kinase binding, this GO :0030296 : protein tyrosine kinase activator activity, this GO :0042802 : identical protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901 : protein kinase binding and also this GO :0030296 : protein tyrosine kinase activator activity and also this GO :0042802 : identical protein binding, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030296 and protein tyrosine kinase activator activity and molecular function this GO :0031295 and T cell costimulation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0040008 and regulation of growth and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001271 and negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis and biological process, p21 protein (Cdc42/Rac)-activated kinase 2 |
| Identity: |
8591 |
| Gene: |
PAK2 |
More about : PAK2 |
| Long gene name: |
p21 (RAC1) activated kinase 2 |
| Synonyms gene name: |
p21 (CDKN1A)-activated kinase 2 p21 protein (Cdc42/Rac)-activated kinase 2 |
| Synonyms: |
PAK65 PAKgamma |
| Synonyms name: |
S6/H4 kinase |
| Locus: |
3q29 |
| Discovery year: |
1998-03-25 |
| GenBank acession: |
U24153 |
| Entrez gene record: |
5062 |
| Pubmed identfication: |
7744004 7618083 |
| RefSeq identity: |
NM_002577 |
| Havana BLAST/BLAT: |
OTTHUMG00000155534 |