| Long name: |
Biotin Conjugated, Met (c-Met) (Tyr1003) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Met c-Met Tyr1003 |
| Specificity: |
This is a highly specific antibody against Met c-Met Tyr1003 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr1003 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Met around the phosphorylation site of Tyr1003 |
| Gene ID number: |
4233 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
AKT, Cbl, Cells expressing c-Met include epithelial cells, Crk, ERK1 and 2, FAK, GAB1, HGF/SF stimulation of c-Met expressing cells enhances proliferation, In addition to cancer studies, JNK, Many types of cancer exhibit sustained c-Met stimulation, PI3K, PLC gamma, Ras, Shc, Signaling proteins that are phosphorylated and/or localized in response to c-Met phosphorylation include: Grb2, Src, The mature c-Met protein is a disulfide-linked heterodimer with Mr=190 kDa composed of a heavily glycosylated alpha subunit that is completely extracellular in localization, a member of the tyrosine kinase superfamily, a single transmembrane domain, also known as scatter factor (HGF/SF), and STAT3, and a beta subunit comprising an extracellular ligand binding domain, and a cytoplasmic tyrosine kinase domain, and glomerular mesenchymal cells, and protease synthesis, angiogenesis and surgical wound healing, as well as melanomas and sarcomas, blood cells of various types, breast, characteristics that are associated with invasive cell phenotype, cortactin, endothelial cells, including carcinomas of the colon, is the receptor for hepatocyte growth factor, kidney, liver, lung, migration, morphogenesis, or mutation, organ regeneration, other research areas in which c-Met is under investigation include organogenesis, ovary, overexpression, paxillin, prostate, thyroid, &euro, &trade, HGF/SF binding to c-Met stimulates receptor dimerization and the phosphorylation of numerous residues within the receptorâ, c-Met, s cytoplasmic domain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
AUTS9, D249, HGF, HGF SF receptor, HGF receptor, HGF/SF receptor, HGFR, Hepatocyte growth factor receptor, Hepatocyte growth factor receptor Precursor, MET, MET_HUMAN, Met proto oncogene tyrosine kinase, Met proto-oncogene, Met proto-oncogene hepatocyte growth factor receptor, Met protooncogene, Oncogene MET, Par4, Proto-oncogene c-Met, RCCP2, Renal cell carcinoma papillary 2 gene, SF receptor, Scatter factor receptor, Tyrosine-protein kinase Met, c met, cmet, Met c-Met Tyr1003 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Met (c-Met) (Tyr1003) Conjugated |
| Short name: |
Conjugated, Met (c-Met) (Tyr1003) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Met (c-Met) (Tyr1003) (Antibody to) |
| Alternative technique: |
antibodies |