| Long name: |
MEK1/2(Ser218 + Ser222) Antibody |
| Also known as: |
MEK1/2(Ser218 + Ser222) Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MEK1/2 Ser218 + Ser222 |
| Specificity: |
These phosphorylation sites are homologous to Ser222 + Ser226 in MEK2 and are the same across the listed species, This is a highly specific antibody against MEK1/2 Ser218 + Ser222 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser218 + Ser222 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
180-230/393 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human MEK1 around the phosphorylation site of Ser218/222 |
| Gene ID number: |
56045605 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
As an essential component of MAP kinase signal transduction pathway, MAP kinases, This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals, act as an integration point for multiple biochemical signals, also known as extracellular signal-regulated kinases (ERKs), differentiation, this kinase is involved in many cellular processes such as proliferation, transcription regulation and development, which acts as a mitogen-activated protein (MAP) kinase kinase, The protein encoded by this gene is a member of the dual specificity protein kinase family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Dual specicity mitogen activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1, MAP kinase/Erk kinase 1, MAP/Erk kinase 1, MAPK/ERK kinase 1, MAPKK 1, MAPKK1, MEK 1, MEKK1, MKK 1, MKK1, Map2K1, Mitogen activated protein kinase kinase 1, PRKMK 1, PRKMK1, Protein kinase mitogen activated, Protein kinase mitogen activated kinase 1, kinase 1, MAP2K1phospho S218/S222, Protein kinase mitogen activated kinase 1 MAP kinase kinase 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MEK1/2(Ser218 + Ser222) |
| Short name: |
MEK1/2(Ser218 + Ser222) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MEK1/2(Ser218 and Ser222) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6840 |
| Gene: |
MAP2K1 |
More about : MAP2K1 |
| Long gene name: |
mitogen-activated protein kinase kinase 1 |
| Synonyms gene: |
PRKMK1 |
| Synonyms: |
MEK1 MAPKK1 |
| Locus: |
15q22, 31 |
| Discovery year: |
1993-11-05 |
| GenBank acession: |
L11284 |
| Entrez gene record: |
5604 |
| Pubmed identfication: |
9465908 8388392 |
| Classification: |
Mitogen-activated protein kinase kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000133196 |
| Locus Specific Databases: |
The Globin Gene Server LRG_725 |