| Long name: |
Cy5 Conjugated, MEF2A (Ser408) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MEF2A Ser408 |
| Specificity: |
This is a highly specific antibody against MEF2A Ser408 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser408 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
380-425/507 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human MEF2A around the phosphorylation site of Ser408 |
| Gene ID number: |
4205 |
| Swiss Prot: |
Q02078 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
5'-YTA[AT](4)TAR-3', Also involved in the activation of numerous growth factor- and stress-induced genes, Associates with chromatin to the ZNF16 promoter, In cerebellar granule neurons, Mediates cellular functions not only in skeletal and cardiac muscle development, Plays diverse roles in the control of cell growth, but also in neuronal differentiation and survival, found in numerous muscle-specific genes, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription, Transcriptional activator which binds specifically to the MEF2 element |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
625, 650nm/670nm |
| Synonyms: |
RSRFC4 RSRFC9 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MEF2A (Ser408) Conjugated |
| Short name: |
Conjugated, MEF2A (Ser408) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy5 |
| Alternative name: |
cyanine 5 coupled, myocyte enhancer factor 2A (Ser408) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADCAD1 and mef2 and RSRFC4 and RSRFC9, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0007507 and heart development and biological process this GO :0007517 and muscle organ development and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0033613 and activating transcription factor binding and molecular function this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034162 and toll-like receptor 9 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0035035 and histone acetyltransferase binding and molecular function this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0042692 and muscle cell differentiation and biological process this GO :0042826 and histone deacetylase binding and molecular function this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046982 and protein heterodimerization activity and molecular function this GO :0046983 and protein dimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048311 and mitochondrion distribution and biological process this GO :0048813 and dendrite morphogenesis and biological process this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0051403 and stress-activated MAPK cascade and biological process this GO :0055005 and ventricular cardiac myofibril assembly and biological process this GO :0061337 and cardiac conduction and biological process this GO :0070375 and ERK5 cascade and biological process this GO :0071277 and cellular response to calcium ion and biological process, MEF2A and IDBG-31725 and ENSG00000068305 and 4205, MEF2A and IDBG-628642 and ENSBTAG00000010649 and 407231, Mef2a and IDBG-192076 and ENSMUSG00000030557 and 17258, nuclei, protein dimerization activity, this GO :0000002 and mitochondrial genome maintenance and biological process this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000165 and MAPK cascade and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001085 and RNA polymerase II transcription factor binding and molecular function this GO :0001105 and RNA polymerase II transcription coactivator activity and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006351 and transcription, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001085 : RNA polymerase II transcription factor binding and also this GO :0001105 : RNA polymerase II transcription coactivator activity and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0033613 : activating transcription factor binding and also this GO :0035035 : histone acetyltransferase binding and also this GO :0042826 : histone deacetylase binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046332 : SMAD binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0046983 : protein dimerization activity, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001085 : RNA polymerase II transcription factor binding, this GO :0001105 : RNA polymerase II transcription coactivator activity, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, this GO :0033613 : activating transcription factor binding, this GO :0035035 : histone acetyltransferase binding, this GO :0042826 : histone deacetylase binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046332 : SMAD binding, this GO :0046982 : protein heterodimerization activity, this GO :0046983 : protein dimerization activity, myocyte enhancer factor 2A |
| Identity: |
6993 |
| Gene: |
MEF2A |
More about : MEF2A |
| Long gene name: |
myocyte enhancer factor 2A |
| Locus: |
15q26, 3 |
| Discovery year: |
1995-02-08 |
| Entrez gene record: |
4205 |
| Pubmed identfication: |
1516833 |
| Classification: |
Myocyte enhancer factor 2 proteins MADS box family |
| Havana BLAST/BLAT: |
OTTHUMG00000171937 |