HER3 (Tyr1197) Antibody, Cy5 Conjugated

Catalog number:	bs-3218R-Cy5 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	HER3 (Tyr1197) Antibody, Cy5 Conjugated
Quantity:	100ul
Related search:	antibody erbb antibodies receptor synonyms tyrosine congenital

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Long name:	Cy5 Conjugated, HER3 (Tyr1197) Polyclonal Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	HER3 Tyr1197
Specificity:	This is a highly specific antibody against HER3 Tyr1197
Modification:	Phosphorylation
Modification site:	Tyr1197
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human HER3 around the phosphorylation site of Tyr1197 [EE(p-Y)EY]
Gene ID number:	2065
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Additional splice variants have also been reported but they have not been thoroughly characterized, Alternate transcriptional splice variants encoding different isoforms have been characterized, Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers including prostate, Defects in ERBB3 are the cause of lethal congenital contracture syndrome type 2 (LCCS2), ErbB3 is a membrane-bound protein which has a neuregulin binding domain but not an active kinase domain, Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation, However it does form heterodimers with other EGF receptor family members which do have kinase activity, Isoform 2 lacks the intermembrane region and is secreted outside the cell, It can therefore bind this ligand but cannot convey a signal into the cell via protein phosphorylation, LCCS2 is an autosomal recessive neurogenic form of a neonatally lethal arthrogryposis that is associated with atrophy of the anterior horn of the spinal cord, This form acts to modulate the activity of the membrane-bound form, also called Israeli Bedouin multiple contracture syndrome type A, bladder and breast tumors, ErbB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	625, 650nm/670nm
Synonyms:	HER3
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	HER3 (Tyr1197) Conjugated
Short name:	Conjugated, HER3 (Tyr1197) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy5
Alternative name:	cyanine 5 coupled, HER3 (Tyr1197) (Antibody to)
Alternative technique:	antibodies
Identity:	3431
Gene:	ERBB3 | More about : ERBB3
Long gene name:	erb-b2 receptor tyrosine kinase 3
Synonyms gene:	LCCS2
Synonyms gene name:	lethal congenital contracture syndrome 2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Synonyms name:	human epidermal growth factor receptor 3
Locus:	12q13, 2
Discovery year:	1990-07-15
GenBank acession:	M34309
Entrez gene record:	2065
RefSeq identity:	NM_001982
Classification:	Erb-b2 receptor tyrosine kinases
Havana BLAST/BLAT:	OTTHUMG00000170140
Locus Specific Databases:	LRG_996

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