IRS1(Ser636 + Ser639) Antibody, Cy5 Conjugated

Catalog number:	bs-3201R-Cy5 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies
Product name:	IRS1(Ser636 + Ser639) Antibody, Cy5 Conjugated
Quantity:	0.1ml
Related search:	process biological binding insulin kinase protein regulation signaling cellular positive pathway component growth factor response domain phosphorylation

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Long name:	Cy5 Conjugated, IRS1(Ser636 + Ser639) Antibody
Category:	Conjugated Primary Antibodies
Conjugation:	5, Cy5
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	IRS1 Ser636 + Ser639
Specificity:	Ser675 + Ser678 in Mouse, This phosphorylation site is homologous to Ser632 + ser635 in Mouse and Rat IRS1, This protein is known to be highly conserved in this sequences region, and Ser676 +Ser679 in Rat based on homology, this antibody may react with IRS2 when phosphorylated at Ser679 + Ser682 in Human , thus , This is a highly specific antibody against IRS1 Ser636 + Ser639
Modification:	Phosphorylation
Modification site:	Ser636 + Ser639
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Immunogen_range:	610-660/1242
Subcellular location:	Membrane bound, Nucleus, Cytoplasm
Source:	KLH conjugated synthetic phosphopeptide derived from human IRS1 around the phosphorylation site of Ser636/639 [PM(p-S)PK(p-S)VS]
Gene ID number:	3667
Swiss Prot:	P35568
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Crossreactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background:	Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity), When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2, May mediate the control of various cellular processes by insulin
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission:	625, 650nm/670nm
Synonyms:	HIRS-1
Properties:	Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target:	IRS1(Ser636 + Ser639) Conjugated
Short name:	Conjugated, IRS1(Ser636 + Ser639) Antibody
Technique:	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label:	Cy5
Alternative name:	cyanine 5 coupled, insulin receptor substrate 1(Ser636 and Ser639) (Antibody to)
Alternative technique:	antibodies
Alternative to gene target:	HIRS-1, IRS1 and IDBG-647770 and ENSBTAG00000021308 and 538598, IRS1 and IDBG-82407 and ENSG00000169047 and 3667, Irs1 and IDBG-173589 and ENSMUSG00000055980 and 16367, nuclei, phosphatidylinositol 3-kinase binding, this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005068 and transmembrane receptor protein tyrosine kinase adaptor activity and molecular function this GO :0005080 and protein kinase C binding and molecular function this GO :0005158 and insulin receptor binding and molecular function this GO :0005159 and insulin-like growth factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005899 and insulin receptor complex and cellular component this GO :0005901 and caveola and cellular component this GO :0007165 and signal transduction and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010907 and positive regulation of glucose metabolic process and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0016042 and lipid catabolic process and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0030335 and positive regulation of cell migration and biological process this GO :0030879 and mammary gland development and biological process this GO :0032000 and positive regulation of fatty acid beta-oxidation and biological process this GO :0032868 and response to insulin and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0034504 and protein localization to nucleus and biological process this GO :0036064 and ciliary basal body and cellular component this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042593 and glucose homeostasis and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043434 and response to peptide hormone and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043548 and phosphatidylinositol 3-kinase binding and molecular function this GO :0043552 and positive regulation of phosphatidylinositol 3-kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045725 and positive regulation of glycogen biosynthetic process and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0046627 and negative regulation of insulin receptor signaling pathway and biological process this GO :0046628 and positive regulation of insulin receptor signaling pathway and biological process this GO :0046676 and negative regulation of insulin secretion and biological process this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :2001275 and positive regulation of glucose import in response to insulin stimulus and biological process, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity and also this GO :0005080 : protein kinase C binding and also this GO :0005158 : insulin receptor binding and also this GO :0005159 : insulin-like growth factor receptor binding and also this GO :0005515 : protein binding and also this GO :0019901 : protein kinase binding and also this GO :0042169 : SH2 domain binding and also this GO :0043548 : phosphatidylinositol 3-kinase binding, this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity, this GO :0005080 : protein kinase C binding, this GO :0005158 : insulin receptor binding, this GO :0005159 : insulin-like growth factor receptor binding, this GO :0005515 : protein binding, this GO :0019901 : protein kinase binding, this GO :0042169 : SH2 domain binding, this GO :0043548 : phosphatidylinositol 3-kinase binding, insulin receptor substrate 1
Identity:	6125
Gene:	IRS1 | More about : IRS1
Long gene name:	insulin receptor substrate 1
Locus:	2q36, 3
Discovery year:	1992-08-24
Entrez gene record:	3667
Pubmed identfication:	1648180
RefSeq identity:	NM_005544
Classification:	Pleckstrin homology domain containing
Havana BLAST/BLAT:	OTTHUMG00000133179

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• #pathway
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• #growth
• #factor
• #response
• #domain
• #phosphorylation