GAB2 (Ser623) Antibody, ALEXA FLUOR 594

Catalog number:	bs-3183R-A594 Buy Now
Price:	350 €
Supplier:	Bioss Primary Conjugated Antibodies.
Product name:	GAB2 (Ser623) Antibody, ALEXA FLUOR 594
Quantity:	100ul
Related search:	protein gab binding alexa ser process phosphatidylinositol activity function kinase regulation

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Long name:	ALEXA FLUOR 594 Conjugated, GAB2 (Ser623) Polyclonal Antibody
Also known as:	Anti-GAB2 Ser623 PAb ALEXA FLUOR 594
Category:	Conjugated Primary Antibodies
Conjugated with:	594, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	GAB2 Ser623
Specificity:	This is a highly specific antibody against GAB2 Ser623
Modification:	Phosphorylation
Modification Site:	Ser623
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human GAB2 around the phosphorylation site of Ser623
Gene ID Number:	9846
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Mouse, Rat, Human
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	CrkL and SHC, Gab2 acts as a docking protein for several SH2-containing proteins, Gab2 interacts with SHP2 tyrosine phosphatase and GRB2 adaptor protein PI3-kinase, Gab2 is a substrate of various RTKs, Upon tyrosine phosphorylation, cytokine receptors as well as B and T cell antigen receptors, growth factors and cytokines, including EGFR, insulin receptor, Gab2 (Grb2-associated binder-2) is an adaptor protein involved in numerous intracellular signaling pathways via its interaction with receptor tyrosine kinases (RTKs)
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	590nm/617nm
Synonyms:	KIAA0571
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	594, ALEXA FLUOR®, Alexa Fluor
Conjugated:	Alexa conjugate 1
Gene target:	GAB2 (Ser623)
Short name:	GAB2 (Ser623) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 594
Alternative name:	ALEXA FLUOR 594, GRB2-associated binding protein 2 (Ser623) (Antibody to)
Alternative technique:	antibodies
Alternative to gene target:	GAB2 and IDBG-65975 and ENSG00000033327 and 9846, Plasma membranes, phosphatidylinositol-3, this GO :0005068 and transmembrane receptor protein tyrosine kinase adaptor activity and molecular function this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005547 and phosphatidylinositol-3, this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity, this GO :0005068 : transmembrane receptor protein tyrosine kinase adaptor activity and also this GO :0005070 : SH3/SH2 adaptor activity and also this GO :0005515 : protein binding and also this GO :0005547 : phosphatidylinositol-3, this GO :0005070 : SH3/SH2 adaptor activity, this GO :0005515 : protein binding, this GO :0005547 : phosphatidylinositol-3, this GO :0043325 : phosphatidylinositol-3, 4, 4, 4, 4-bisphosphate binding, 4-bisphosphate binding, 4-bisphosphate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process, 5-trisphosphate binding, 5-trisphosphate binding and also this GO :0043325 : phosphatidylinositol-3, 5-trisphosphate binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009967 and positive regulation of signal transduction and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0043306 and positive regulation of mast cell degranulation and biological process this GO :0043325 and phosphatidylinositol-3, GRB2-associated binding protein 2
Identity:	14458
Gene:	GAB2 | More about : GAB2
Long gene name:	GRB2 associated binding protein 2
Synonyms name:	Grb2-associated binder 2
Locus:	11q14, 1
Discovery year:	2001-01-24
GenBank acession:	AB011143
Entrez gene record:	9846
Pubmed identfication:	10391903 10068651
RefSeq identity:	NM_080491
Classification:	Pleckstrin homology domain containing
Havana BLAST/BLAT:	OTTHUMG00000166673

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