| Long name: |
c-Jun (Ser73) Primary Polyclonal Antibody |
| Also known as: |
c-Jun (Ser73) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
c-Jun Ser73 |
| Specificity: |
This is a highly specific antibody against c-Jun Ser73 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser73 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Jun around the phosphorylation site of Ser73 |
| Gene ID number: |
3725 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Extracellular signals including growth factors, In addition, Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways, SAPK/JNK, The MAP kinase homologue, The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription, C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AP 1, AP-1, AP1, Activator 1, Activator Protein 1, Enhancer Binding Protein AP1, JUN, JUN protein, JUNC, JUN_HUMAN, Jun Activation Domain Binding Protein, Jun oncogene, Proto oncogene cJun, Proto-oncogene c-Jun, Transcription Factor AP1, Transcription factor AP-1, V jun avian sarcoma virus 17 oncogene homolog, V-jun avian sarcoma virus 17 oncogene homolog, p-c-Jun phospho S73 , p39, vJun Avian Sarcoma Virus 17 Oncogene Homolog, c-Jun phospho S73 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
c-Jun (Ser73) |
| Short name: |
c-Jun (Ser73) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
c-jun proto-oncogene (Ser73) (Antibody to) |
| Alternative technique: |
antibodies |