| Long name: |
4(Thr18) Primary Polyclonal Antibody, Histone H1 |
| Also known as: |
4(Thr18) PAb, Histone H1 |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
4 Thr18, Histone H1 |
| Specificity: |
Due to the highly conserved nature of these histones, This phosphorylation site is found in Rat H1C as well, This phosphorylation site is homologous to Thr18 in Rat H1C/H1D and Mouse H1D, but not Human or Mouse H1C, this antibody may react with these members when phosphorylated at this site, 4 Thr18, This is a highly specific antibody against Histone H1 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Thr18 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
2-30/219 |
| Subcellular location: |
Nucleus |
| Source: |
4 around the phosphorylation site of Thr18, KLH conjugated synthetic phosphopeptide derived from human Histone H1 |
| Gene ID number: |
3008 |
| Swiss Prot: |
P10412 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts also as a regulator of individual gene transcription through chromatin remodeling, Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers, nucleosome spacing and DNA methylation (By similarity), Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
H1, H1F4, H1s-4, HIST1H1E, Histone H1, Histone H1b, Histone H1s-4, dJ221C16, 4, 4, 5, H1E |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
4(Thr18), Histone H1 |
| Short name: |
4(Thr18) Antibody, Histone H1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
4(Thr18) (Antibody to), Histone H1 |
| Alternative technique: |
antibodies |
| Identity: |
4718 |
| Gene: |
HIST1H1E |
More about : HIST1H1E |
| Long gene name: |
histone cluster 1 H1 family member e |
| Synonyms gene: |
H1F4 |
| Synonyms gene name: |
H1 histone family, H1e , H1e histone cluster 1, member 4 histone 1 |
| Synonyms: |
H1, 4 H1e H1s-4 |
| Locus: |
6p22, 2 |
| Discovery year: |
1988-08-31 |
| GenBank acession: |
M60748 |
| Entrez gene record: |
3008 |
| Pubmed identfication: |
1916825 12408966 |
| RefSeq identity: |
NM_005321 |
| Classification: |
Histones |
| Havana BLAST/BLAT: |
OTTHUMG00000014422 |