| Long name: |
FAK (Tyr407) Primary Polyclonal Antibody |
| Also known as: |
FAK (Tyr407) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
FAK Tyr407 |
| Specificity: |
This is a highly specific antibody against FAK Tyr407 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Tyr407 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Tyr407 |
| Gene ID number: |
5747 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, Cell membrane, Cytoplasmic side, Note=Constituent of focal adhesions, Peripheral membrane protein, Plays a potential role in oncogenic transformations resulting in increased kinase activity, [SUBCELLULAR LOCATION] Cell junction, focal adhesion, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy, proliferation and apoptosis, Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FADK, FADK 1, FAK 1, FAK related non kinase polypeptide, FAK1, FAK1_HUMAN, FRNK, Focal adhesion kinase 1, Focal adhesion kinase-related nonkinase, PPP1R71, PTK 2, Protein Tyrosine Kinase Cytoplasmic, Protein phosphatase 1 regulatory subunit 71, Protein tyrosine kinase 2, Protein-tyrosine kinase 2, p-FAK phospho Y407, p125FAK, pp125FAK, FAK phospho Y407 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FAK (Tyr407) |
| Short name: |
FAK (Tyr407) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
FAK (Tyr407) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9611 |
| Gene: |
PTK2 |
More about : PTK2 |
| Long gene name: |
protein tyrosine kinase 2 |
| Synonyms gene name: |
PTK2 protein tyrosine kinase 2 |
| Synonyms: |
FAK FADK FAK1 PPP1R71 |
| Synonyms name: |
protein phosphatase 1, regulatory subunit 71 |
| Locus: |
8q24, 3 |
| Discovery year: |
1992-10-02 |
| GenBank acession: |
L13616 |
| Entrez gene record: |
5747 |
| Pubmed identfication: |
8422239 |
| RefSeq identity: |
NM_005607 |
| Classification: |
Protein phosphatase 1 regulatory subunits FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000067438 |