| Long name: |
FITC Conjugated, FOXO4/FOXO1 (Ser197/Ser256) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FOXO4/FOXO1 Ser197/Ser256 |
| Specificity: |
This is a highly specific antibody against FOXO4/FOXO1 Ser197/Ser256 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser197/Ser256 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human FOXO4 around the phosphorylation site of Ser197 |
| Gene ID number: |
4303 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, Jan 2010], Multiple transcript variants encoding different isoforms have been found for this gene, Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes, [provided by RefSeq, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia, This gene encodes a member of the O class of winged helix/forkhead transcription factor family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
AFX1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FOXO4/FOXO1 (Ser197/Ser256) Conjugated |
| Short name: |
FITC Conjugated, FOXO4/FOXO1 (Ser197/Ser256) Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, FOXO4/forkhead box O1 (Ser197/Ser256) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006473 and protein acetylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008286 and insulin receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0010508 and positive regulation of autophagy and biological process this GO :0031018 and endocrine pancreas development and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032873 and negative regulation of stress-activated MAPK cascade and biological process this GO :0034599 and cellular response to oxidative stress and biological process this GO :0035947 and regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042593 and glucose homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045444 and fat cell differentiation and biological process this GO :0045599 and negative regulation of fat cell differentiation and biological process this GO :0045722 and positive regulation of gluconeogenesis and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0051721 and protein phosphatase 2A binding and molecular function this GO :0070417 and cellular response to cold and biological process this GO :0071455 and cellular response to hyperoxia and biological process this GO :0071732 and cellular response to nitric oxide and biological process this GO :2000505 and regulation of energy homeostasis and biological process, FKH1 and FKHR and FOXO1A, FOXO1 and IDBG-26475 and ENSG00000150907 and 2308, FOXO1 and IDBG-629639 and ENSBTAG00000044105 and 506618, Foxo1 and IDBG-143370 and ENSMUSG00000044167 and 56458, nuclei, protein phosphatase 2A binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000989 and transcription factor binding transcription factor activity and molecular function this GO :0001078 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and molecular function this GO :0001568 and blood vessel development and biological process this GO :0001659 and temperature homeostasis and biological process this GO :0001678 and cellular glucose homeostasis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006351 and transcription, this GO :0000989 : transcription factor binding transcription factor activity, this GO :0000989 : transcription factor binding transcription factor activity and also this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0051721 : protein phosphatase 2A binding, this GO :0001078 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0043565 : sequence-specific DNA binding, this GO :0051721 : protein phosphatase 2A binding, forkhead box O1 |
| Identity: |
7139 |
| Gene: |
FOXO4 |
More about : FOXO4 |
| Long gene name: |
forkhead box O4 |
| Synonyms gene: |
MLLT7 |
| Synonyms gene name: |
7 , 7 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog), translocated to, translocated to |
| Locus: |
Xq13, 1 |
| Discovery year: |
1994-12-14 |
| Entrez gene record: |
4303 |
| Pubmed identfication: |
7529552 |
| RefSeq identity: |
NM_005938 |
| Classification: |
Forkhead boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000021789 |
| Locus Specific Databases: |
Mental Retardation database |