| Long name: |
Cyclin D1 (Thr286) Primary Polyclonal Antibody |
| Also known as: |
Cyclin D1 (Thr286) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Cyclin D1 Thr286 |
| Specificity: |
This is a highly specific antibody against Cyclin D1 Thr286 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Thr286 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Cyclin D1 around the phosphorylation site of Thr286 |
| Gene ID number: |
595 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, Jul 2008], Mutations, This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb, [provided by RefSeq, amplification and overexpression of this gene, are observed frequently in a variety of tumors and may contribute to tumorigenesis, which alters cell cycle progression, whose activity is required for cell cycle G1/S transition, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle, The protein encoded by this gene belongs to the highly conserved cyclin family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AI327039, B cell ccl/lymphoma 1, B cell leukemia 1, B-cell CLL/lymphoma 1, B-cell leukemia 1, B-cell lymphoma 1 protein, BCL-1, BCL1, BCL1 oncogene, CCND 1, CCND1, CCND1 protein, CCND1/FSTL3 fusion gene, CCND1/IGHG1 fusion gene, CCND1/IGHG1 fusion gene, CCND1/IGLC1 fusion gene, CCND1/PTH fusion gene, CCND1_HUMAN, Cyclin D1, Cyl-1, D11S287E, G1/S specic cyclin D1, MGC137744, PRAD1, PRAD1 oncogene, Parathyroid adenomatosis 1, U21B31, cD1, included, included, included, included, p-Cyclin D1 phospho T286, Cyclin D1 phospho T286 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Cyclin D1 (Thr286) |
| Short name: |
Cyclin D1 (Thr286) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cyclin D1 (Thr286) (Antibody to) |
| Alternative technique: |
antibodies |