| Long name: |
Caspase-9 (Thr125) Primary Polyclonal Antibody |
| Also known as: |
Caspase-9 (Thr125) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Caspase-9 Thr125 |
| Specificity: |
This phosphorylation site is homologous to that of Thr163 in Mouse, This is a highly specific antibody against Caspase-9 Thr125 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Thr125 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
100-150/416 |
| Subcellular location: |
Mitochondrion, Nucleus, Cytoplasm |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human Caspase-9 around the phosphorylation site of Thr125 |
| Gene ID number: |
842 |
| Swiss Prot: |
P55211 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3, Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9, Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, Proteolytically cleaves poly(ADP-ribose) polymerase (PARP), Involved in the activation cascade of caspases responsible for apoptosis execution |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APAF-3, APAF3, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, Caspase-9, ICE-LAP6, ICE-like apoptotic protease 6, PPP1R56, MCH6 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Caspase-9 (Thr125) |
| Short name: |
Caspase-9 (Thr125) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
caspase-9 (Thr125) (Antibody to) |
| Alternative technique: |
antibodies |