| Long name: |
Biotin Conjugated, Amyloid Precursor Protein (T743) Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Amyloid Precursor Protein Thr743 |
| Specificity: |
This is a highly specific antibody against Amyloid Precursor Protein Thr743 |
| Modification: |
Phosphorylation |
| Modification site: |
Thr743 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human APP around the phosphorylation site of Thr743 |
| Gene ID number: |
351 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Jul 2008], Multiple transcript variants encoding several different isoforms have been found for this gene, Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy), Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, [provided by RefSeq, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease, This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
APP Thr743, Amyloid Precursor Protein phospho Thr743, p-Amyloid Precursor Protein phospho Thr743, Amyloid Precursor Protein phospho Thr743 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Description: |
also called a , is a type of partially differentiated, usually , Precursor cell, blast, blast cell , cell that has lost most or all of the , multipotency, or simply , stem cell , unipotent |
| Gene target: |
Amyloid Precursor Protein (T743) Conjugated |
| Short name: |
Conjugated, Amyloid Protein (T743) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Amyloid Precursor Protein (T743) (Antibody to) |
| Alternative technique: |
antibodies |