| Long name: |
Calsequestrin Primary Polyclonal Antibody |
| Also known as: |
Calsequestrin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Calsequestrin |
| Specificity: |
This is a highly specific antibody against Calsequestrin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Calsequestrin |
| Gene ID number: |
844 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor, Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR, Several intralumenal SR calcium binding proteins have been identified, This protein is highly acidic and has a large capacity and moderate to low affinity for calcium, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium, the most prominent of these is calsequestrin, The sarcoplasmic reticulum (SR) is |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CASQ 1, Calsequestrin 1, Calsequestrin 1 fast twitch skeletal muscle, Calsequestrin skeletal muscle isoform, PDIB1, Skeletal muscle calsequestrin 1, CASQ |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Calsequestrin |
| Short name: |
Calsequestrin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Calsequestrin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1513 |
| Gene: |
CASQ2 |
More about : CASQ2 |
| Long gene name: |
calsequestrin 2 |
| Synonyms gene name: |
calsequestrin 2 (cardiac muscle) |
| Synonyms: |
PDIB2 |
| Locus: |
1p13, 1 |
| Discovery year: |
1992-11-05 |
| GenBank acession: |
BC022288 |
| Entrez gene record: |
845 |
| Pubmed identfication: |
8406504 |
| RefSeq identity: |
NM_001232 |
| Classification: |
Protein disulfide isomerases |
| Havana BLAST/BLAT: |
OTTHUMG00000011970 |
| Locus Specific Databases: |
LRG_404 |