| Long name: |
FITC Conjugated, SRPK1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SRPK1 |
| Specificity: |
This is a highly specific antibody against SRPK1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SRPK1 |
| Gene ID number: |
6732 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids, Hyperphosphorylates RS domain-containing proteins such as SFRS1, Locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis, Plays a central role in the regulatory network for splicing |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
SFRSK1 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SRPK1 Conjugated |
| Short name: |
FITC Conjugated, SRPK1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SRSF protein kinase 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
SFRSK1, SRPK1 and IDBG-629997 and ENSBTAG00000016838 and 512631, SRPK1 and IDBG-84414 and ENSG00000096063 and 6732, Srpk1 and IDBG-158718 and ENSMUSG00000004865 and 20815, nuclei, this GO :0000287 and magnesium ion binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005783 and endoplasmic reticulum and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006397 and mRNA processing and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007059 and chromosome segregation and biological process this GO :0008380 and RNA splicing and biological process this GO :0016032 and viral process and biological process this GO :0016363 and nuclear matrix and cellular component this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0044822 : poly(A) RNA binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0044822 : poly(A) RNA binding, transferring phosphorus-containing groups and molecular function this GO :0035092 and sperm chromatin condensation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045070 and positive regulation of viral genome replication and biological process this GO :0045071 and negative regulation of viral genome replication and biological process this GO :0045087 and innate immune response and biological process this GO :0048024 and regulation of mRNA splicing, via spliceosome and biological process this GO :0050684 and regulation of mRNA processing and biological process, SRSF protein kinase 1 |
| Identity: |
11305 |
| Gene: |
SRPK1 |
More about : SRPK1 |
| Long gene name: |
SRSF protein kinase 1 |
| Synonyms gene name: |
SFRS protein kinase 1 |
| Synonyms name: |
SR protein kinase 1 serine/arginine-rich splicing factor kinase 1 |
| Locus: |
6p21, 31 |
| Discovery year: |
1998-03-02 |
| GenBank acession: |
U09564 |
| Entrez gene record: |
6732 |
| Pubmed identfication: |
8208298 10198174 |
| RefSeq identity: |
NM_003137 |
| Havana BLAST/BLAT: |
OTTHUMG00000014583 |