| Long name: |
Recombinant Human Tumor necrosis factor ligand superfamily member 11 (TNFSF11) |
| Alternative names: |
CD_antigen: CD254Cleaved into the following 2 chains:Tumor necrosis factor ligand superfamily member 11, ODF, OPGL, Osteoclast differentiation factor, Osteoprotegerin ligand, RANKL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TNF-related activation-induced cytokine, TRANCE, Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor ligand superfamily member 11, member 11, membrane form, osteoclast differentiation factor, osteoprotegerin ligand, receptor activator of nuclear factor kappa B ligand, receptor activator of nuclear factor kappa-B ligand, soluble form, tumor necrosis factor (ligand) superfamily, tumor necrosis factor ligand superfamily member 11, tumor necrosis factor ligand superfamily member 11 isoform 1 |
| Gene name: |
TNFSF11 |
| Other gene names: |
CD254, ODF, ODF, OPGL, OPGL, OPGL, OPTB2, RANKL, RANKL, RANKL, TNFSF11, TRANCE, TRANCE, TRANCE, hRANKL2, sOdf, TNFSF11 |
| General description: |
All of our recombinant proteins are manufactured in strictly controlled facilities and by using a well established technology which guarantees full batch-to-bact consistency and experiment reproducibility, The protein can be with or without a His-Tag or other tag in accordance to customer's request, Tumor necrosis factor ligand superfamily member 11(TNFSF11) is a recombinant protein expressed in Mammalian Cell |
| Product category: |
Recombinant Proteins |
| Expression system: |
Mammalian Cell |
| Available also expressed in:: |
Baculovirus , Mammalian Cell, Yeast , E Coli |
| Purity: |
Greater than 90% (determined by SDS-PAGE) |
| Form: |
Lyophilized protein |
| Storage: |
Avoid cycles of freezing and thawing as they might denaturate the polypeptide chains, For extended periods of time it is recommended to keep the protein frozen at -40 or -80 degrees Celsius, This protein can be stored at -20 degrees Celsius |
| Applications: |
IFA, RIA, Western Blot, etc, This protein can be used as a positive control for applications such as ELISA |
| Description: |
Complex subunit associated factors are involved in hybridoma growth, Eosinohils, NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation, Aplha |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, Homo sapiens sapiens), Human proteins, humans , ssp |
| Gene target: |
Tumor necrosis factor ligand superfamily member 11 (TNFSF11) |
| Short name: |
Tumor necrosis factor ligand superfamily member 11 (TNFSF11) |
| Species: |
Humans, Human |
| Alternative name: |
member 11), sapiens Tumor necrosis factor ligand supergroup member 11 (tumor necrosis factor (ligand) superfamily, H |
| Alternative to gene target: |
CD254 and hRANKL2 and ODF and OPGL and OPTB2 and RANKL and sOdf and TRANCE, Extracellular, TNFSF11 and IDBG-28393 and ENSG00000120659 and 8600, TNFSF11 and IDBG-628731 and ENSBTAG00000008924 and 513836, Tnfsf11 and IDBG-182101 and ENSMUSG00000022015 and 21943, member 11, this GO :0001503 and ossification and biological process this GO :0002158 and osteoclast proliferation and biological process this GO :0002548 and monocyte chemotaxis and biological process this GO :0005125 and cytokine activity and molecular function this GO :0005164 and tumor necrosis factor receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0007257 and activation of JUN kinase activity and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0016020 and membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0032813 and tumor necrosis factor receptor superfamily binding and molecular function this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0033598 and mammary gland epithelial cell proliferation and biological process this GO :0034112 and positive regulation of homotypic cell-cell adhesion and biological process this GO :0042327 and positive regulation of phosphorylation and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043406 and positive regulation of MAP kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0045453 and bone resorption and biological process this GO :0045670 and regulation of osteoclast differentiation and biological process this GO :0045672 and positive regulation of osteoclast differentiation and biological process this GO :0045780 and positive regulation of bone resorption and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046330 and positive regulation of JNK cascade and biological process this GO :0050870 and positive regulation of T cell activation and biological process this GO :0051091 and positive regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051466 and positive regulation of corticotropin-releasing hormone secretion and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0055074 and calcium ion homeostasis and biological process this GO :0060749 and mammary gland alveolus development and biological process this GO :0070371 and ERK1 and ERK2 cascade and biological process this GO :0071812 and positive regulation of fever generation by positive regulation of prostaglandin secretion and biological process this GO :0071847 and TNFSF11-mediated signaling pathway and biological process this GO :0071848 and positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling and biological process this GO :1902533 and positive regulation of intracellular signal transduction and biological process this GO :2001206 and positive regulation of osteoclast development and biological process, this GO :0005125 : cytokine activity, this GO :0005125 : cytokine activity and also this GO :0005164 : tumor necrosis factor receptor binding and also this GO :0005515 : protein binding and also this GO :0032813 : tumor necrosis factor receptor superfamily binding, this GO :0005164 : tumor necrosis factor receptor binding, this GO :0005515 : protein binding, this GO :0032813 : tumor necrosis factor receptor superfamily binding, tumor necrosis factor receptor superfamily binding, tumor necrosis factor (ligand) superfamily |
| Identity: |
11926 |
| Gene: |
TNFSF11 |
More about : TNFSF11 |
| Long gene name: |
tumor necrosis factor superfamily member 11 |
| Synonyms gene name: |
member 11 , tumor necrosis factor (ligand) superfamily |
| Synonyms: |
TRANCE RANKL OPGL ODF CD254 |
| Locus: |
13q14 |
| Discovery year: |
1998-12-04 |
| GenBank acession: |
AF013171 |
| Pubmed identfication: |
9312132 9367155 |
| Classification: |
Tumor necrosis factor superfamily CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000016807 |