| Long name: |
ALEXA FLUOR 488 Conjugated, Aurora A+B+C Polyclonal Antibody |
| Also known as: |
Anti-Aurora A+B+C PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Aurora A+B+C |
| Specificity: |
This is a highly specific antibody against Aurora A+B+C |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Aurora A/B/C |
| Gene ID Number: |
6790 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Aurora A is viewed as a potential target for anticancer drug treatment, Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis, Aurora-C expression is maximum at M phase, Elevated expression levels are seen only in a subset of cancer cells such as HepG2, Expression is limited to testis in normal cells, HuH7 and HeLa cells, It localizes to the inner centromere region from prophase to anaphase, The Aurora kinases, This protein is localized to centrosome from anaphase to cytokinesis, and may regulate several stages of mitosis such as centrosome separation, associate with microtubules during chromosome movement and segregation, behaves as a chromosomal passenger protein, chromosome segregation and cytokinesis, in relation to the function of the centrosome/spindle pole region during chromosome segregation, members of the Ser/Thr protein kinase family, ovarian and colorectal, Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
AIE2, AIK2, AIK3, AIM1, ARK1, ARK2, AURA, AURKA, AURKA_HUMAN, AURKB, AURKC, AURKC, AURORA2, AYK1, AurB, AurC, Aurora 1, Aurora 2, Aurora A, Aurora C, Aurora Family Kinase 1, Aurora Related Kinase 1, Aurora and Ipl1 like midbody associated protein 1, Aurora kinase B, Aurora related kinase 2, Aurora-B, Aurora/IPL1 Like Kinase, Aurora/IPL1 Related Kinase 1, Aurora/IPL1 related kinase 2, Aurora/Ipl1 related kinase 3, Aurora/Ipl1/Eg2 protein 2, BRAK, BTAK, Breast Tumor Amplied Kinase, EC 2, IAK, IPL-1, IPL1, IPL1 Aurora Related Kinase 1, IPL1 Related Kinase, MGC34538, STK1, STK12, STK13, STK5, Serine threonine protein kinase 13, Serine/theronine kinase 12, Serine/threonine protein kinase 12, aurora kinase A, hARK1, 1, 7, 11, AIK |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Aurora A+B+C Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Aurora A+B+C |
| Short name: |
Aurora A+B+C Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Aurora A+B+C (Antibody to) |
| Alternative technique: |
antibodies |