| Long name: |
APS Primary Polyclonal Antibody |
| Also known as: |
APS PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
APS |
| Specificity: |
This is a highly specific antibody against APS |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APS |
| Gene ID number: |
354 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A PH and an SH2 domain containing adaptor protein that links activated tyrosine kinases to signaling pathways, APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl, It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, an adaptor protein that is involved in B cell signaling, chemokines and leukokines, insulin signaling and cytoskeletal reorganisation, APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Adaptor protein with pleckstrin homology and src homology 2 domains, SH2 and PH domain containing adapter protein APS, SH2B2_HUMAN, APS |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APS |
| Short name: |
APS Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
APS (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17381 |
| Gene: |
SH2B2 |
More about : SH2B2 |
| Long gene name: |
SH2B adaptor protein 2 |
| Synonyms: |
APS |
| Synonyms name: |
adaptor protein with pleckstrin homology and src |
| Locus: |
7q22, 1 |
| Discovery year: |
2006-07-04 |
| GenBank acession: |
AB000520 |
| Entrez gene record: |
10603 |
| Pubmed identfication: |
9233773 |
| RefSeq identity: |
NM_020979 |
| Classification: |
Pleckstrin homology domain containing SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000150652 |