| Long name: |
FITC Conjugated, DKK3 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DKK3 |
| Specificity: |
This is a highly specific antibody against DKK3 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
50-85/350 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human DKK3 |
| Gene ID number: |
27122 |
| Swiss Prot: |
Q9UBP4 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
DKKs play an important role in vertebrate development, Dkks are implicated in bone formation and bone disease, In the adult, cancer and Alzheimer disease (By similarity), limb development, somitogenesis and eye formation, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
REIC RIG |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DKK3 Conjugated |
| Short name: |
FITC Conjugated, DKK3 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, DKK3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2893 |
| Gene: |
DKK3 |
More about : DKK3 |
| Long gene name: |
dickkopf WNT signaling pathway inhibitor 3 |
| Synonyms gene name: |
dickkopf (Xenopus laevis) homolog 3 dickkopf 3 homolog (Xenopus laevis) |
| Synonyms name: |
regulated in glioma |
| Locus: |
11p15, 3 |
| Discovery year: |
2000-09-01 |
| GenBank acession: |
AF177396 |
| Entrez gene record: |
27122 |
| Pubmed identfication: |
10570958 |
| RefSeq identity: |
NM_013253 |
| Havana BLAST/BLAT: |
OTTHUMG00000165709 |