| Long name: |
ALEXA FLUOR 488 Conjugated, IL5RA/CD125 Polyclonal Antibody |
| Also known as: |
Anti-IL5RA/CD125 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
IL5RA/CD125 |
| Specificity: |
This is a highly specific antibody against IL5RA/CD125 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL-5R alpha |
| Gene ID Number: |
3568 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Six alternatively spliced transcript variants encoding three distinct isoforms have been reported, The beta subunit is activated by the ligand binding, The binding of this protein to IL5 depends on the beta subunit, The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), This protein has been found to interact with syndecan binding protein (syntenin), and interleukin 5(IL5), and is required for the biological activities of IL5, colony stimulating factor 2 (CSF2/GM-CSF), which is required for IL5 mediated activation of the transcription factor SOX4, The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CDw125 CD125 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the IL5RA/CD125 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
IL5RA/CD125 |
| Short name: |
IL5RA/CD125 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, alpha/CD125 (Antibody to), interleukin 5 receptor |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD125 and CDw125 and HSIL5R3 and IL5R, Extracellular, IL5RA and IDBG-13590 and ENSG00000091181 and 3568, IL5RA and IDBG-644842 and ENSBTAG00000000273 and 615848, Il5ra and IDBG-173890 and ENSMUSG00000005364 and 16192, alpha, protein binding, this GO :0002437 and inflammatory response to antigenic stimulus and biological process this GO :0004896 and cytokine receptor activity and molecular function this GO :0004914 and interleukin-5 receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0008283 and cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0032674 and regulation of interleukin-5 production and biological process this GO :0038043 and interleukin-5-mediated signaling pathway and biological process this GO :0071310 and cellular response to organic substance and biological process, this GO :0004896 : cytokine receptor activity, this GO :0004896 : cytokine receptor activity and also this GO :0004914 : interleukin-5 receptor activity and also this GO :0005515 : protein binding, this GO :0004914 : interleukin-5 receptor activity, this GO :0005515 : protein binding, interleukin 5 receptor |
| Identity: |
6017 |
| Gene: |
IL5RA |
More about : IL5RA |
| Long gene name: |
interleukin 5 receptor subunit alpha |
| Synonyms gene: |
IL5R |
| Synonyms gene name: |
alpha , interleukin 5 receptor |
| Locus: |
3p26, 2 |
| Discovery year: |
1992-06-18 |
| GenBank acession: |
M96652 |
| Entrez gene record: |
3568 |
| Pubmed identfication: |
1732409 |
| Classification: |
CD molecules Interleukin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000090245 |