| Long name: |
FITC Conjugated, CD26 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CD26 |
| Specificity: |
This is a highly specific antibody against CD26 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
659-697/766 |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human CD26 |
| Gene ID number: |
1803 |
| Swiss Prot: |
P27487 |
| Tested applications: |
IF(ICC), IF(IHC-P) |
| Recommended dilutions: |
IF(ICC)(1:50-200), IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Goat, Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, Acts as a positive regulator of T-cell coactivation, CAV1, IGF2R, In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner, Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion, May be involved in the promotion of lymphatic endothelial cells adhesion, Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline, When overexpressed, a process inhibited by GPC3, and PTPRC, by binding at least ADA, enhanced cell proliferation, including many chemokines, migration and tube formation, mitogenic growth factors, neuropeptides and peptide hormones, the migration and invasion of endothelial cells into the ECM, Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
DPPIV |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CD26 Conjugated |
| Short name: |
FITC Conjugated, CD26 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CD26 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3009 |
| Gene: |
DPP4 |
More about : DPP4 |
| Long gene name: |
dipeptidyl peptidase 4 |
| Synonyms gene: |
CD26 ADCP2 |
| Synonyms gene name: |
adenosine deaminase complexing protein 2) adenosine deaminase complexing protein 2 dipeptidyl-peptidase 4 , dipeptidylpeptidase IV (CD26 |
| Locus: |
2q24, 2 |
| Discovery year: |
1990-03-05 |
| GenBank acession: |
M74777 |
| Entrez gene record: |
1803 |
| Pubmed identfication: |
8101391 |
| Classification: |
DASH family CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000132056 |