| Long name: |
FITC Conjugated, CCR5/CD195 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCR5/CD195 |
| Specificity: |
This is a highly specific antibody against CCR5/CD195 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
204-233/352 |
| Subcellular location: |
Helical, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human CCR-5 |
| Gene ID number: |
1234 |
| Swiss Prot: |
P51681 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level, May play a role in the control of granulocytic lineage proliferation or differentiation, Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CKR-5 CC-CKR-5 CKR5 CD195 IDDM22 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCR5/CD195 Conjugated |
| Short name: |
FITC Conjugated, CCR5/CD195 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, chemokine (C-C motif) receptor 5 (gene/pseudogene)/CD195 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CC-CKR-5 and CCCKR5 and CCR-5 and CD195 and CKR-5 and CKR5 and CMKBR5 and IDDM22, CCR5 and IDBG-30229 and ENSG00000160791 and 1234, CCR5 and IDBG-646247 and ENSBTAG00000008099 and 497017, Cell surfaces, chemokine (C-C motif) ligand 5 binding, this GO :0000165 and MAPK cascade and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0003779 and actin binding and molecular function this GO :0004435 and phosphatidylinositol phospholipase C activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006816 and calcium ion transport and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0014808 and release of sequestered calcium ion into cytosol by sarcoplasmic reticulum and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0019722 and calcium-mediated signaling and biological process this GO :0019957 and C-C chemokine binding and molecular function this GO :0023052 and signaling and biological process this GO :0030260 and entry into host cell and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0070723 and response to cholesterol and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071791 and chemokine (C-C motif) ligand 5 binding and molecular function, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0004435 : phosphatidylinositol phospholipase C activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0005515 : protein binding and also this GO :0015026 : coreceptor activity and also this GO :0016493 : C-C chemokine receptor activity and also this GO :0019957 : C-C chemokine binding and also this GO :0071791 : chemokine (C-C motif) ligand 5 binding, this GO :0004435 : phosphatidylinositol phospholipase C activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0005515 : protein binding, this GO :0015026 : coreceptor activity, this GO :0016493 : C-C chemokine receptor activity, this GO :0019957 : C-C chemokine binding, this GO :0071791 : chemokine (C-C motif) ligand 5 binding, chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| Identity: |
1606 |
| Gene: |
CCR5 |
More about : CCR5 |
| Long gene name: |
C-C motif chemokine receptor 5 (gene/pseudogene) |
| Synonyms gene: |
CMKBR5 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 5 chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| Locus: |
3p21, 31 |
| Discovery year: |
1996-05-15 |
| Entrez gene record: |
1234 |
| Pubmed identfication: |
8639485 |
| RefSeq identity: |
NM_000579 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133481 |