| Long name: |
ALEXA FLUOR 594 Conjugated, CCR5/CD195 Polyclonal Antibody |
| Also known as: |
Anti-CCR5/CD195 PAb ALEXA FLUOR 594 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCR5/CD195 |
| Specificity: |
This is a highly specific antibody against CCR5/CD195 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
204-233/352 |
| Subcellular location: |
Helical, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CCR-5 |
| Gene ID Number: |
1234 |
| Swiss Prot: |
P51681 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level, May play a role in the control of granulocytic lineage proliferation or differentiation, Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
CKR-5 CC-CKR-5 CKR5 CD195 IDDM22 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated: |
Alexa conjugate 1 |
| Gene target: |
CCR5/CD195 |
| Short name: |
CCR5/CD195 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 594 |
| Alternative name: |
ALEXA FLUOR 594, chemokine (C-C motif) receptor 5 (gene/pseudogene)/CD195 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CC-CKR-5 and CCCKR5 and CCR-5 and CD195 and CKR-5 and CKR5 and CMKBR5 and IDDM22, CCR5 and IDBG-30229 and ENSG00000160791 and 1234, CCR5 and IDBG-646247 and ENSBTAG00000008099 and 497017, Cell surfaces, chemokine (C-C motif) ligand 5 binding, this GO :0000165 and MAPK cascade and biological process this GO :0002407 and dendritic cell chemotaxis and biological process this GO :0003779 and actin binding and molecular function this GO :0004435 and phosphatidylinositol phospholipase C activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006816 and calcium ion transport and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0014808 and release of sequestered calcium ion into cytosol by sarcoplasmic reticulum and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0019722 and calcium-mediated signaling and biological process this GO :0019957 and C-C chemokine binding and molecular function this GO :0023052 and signaling and biological process this GO :0030260 and entry into host cell and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process this GO :0070723 and response to cholesterol and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071791 and chemokine (C-C motif) ligand 5 binding and molecular function, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0004435 : phosphatidylinositol phospholipase C activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0005515 : protein binding and also this GO :0015026 : coreceptor activity and also this GO :0016493 : C-C chemokine receptor activity and also this GO :0019957 : C-C chemokine binding and also this GO :0071791 : chemokine (C-C motif) ligand 5 binding, this GO :0004435 : phosphatidylinositol phospholipase C activity, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0005515 : protein binding, this GO :0015026 : coreceptor activity, this GO :0016493 : C-C chemokine receptor activity, this GO :0019957 : C-C chemokine binding, this GO :0071791 : chemokine (C-C motif) ligand 5 binding, chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| Identity: |
1606 |
| Gene: |
CCR5 |
More about : CCR5 |
| Long gene name: |
C-C motif chemokine receptor 5 (gene/pseudogene) |
| Synonyms gene: |
CMKBR5 |
| Synonyms gene name: |
chemokine (C-C motif) receptor 5 chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| Locus: |
3p21, 31 |
| Discovery year: |
1996-05-15 |
| Entrez gene record: |
1234 |
| Pubmed identfication: |
8639485 |
| RefSeq identity: |
NM_000579 |
| Classification: |
CD molecules C-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133481 |