| Long name: |
CD43/SPN Primary Polyclonal Antibody |
| Also known as: |
CD43/SPN PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CD43/SPN |
| Specificity: |
This is a highly specific antibody against CD43/SPN |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
277-320/400 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CD43 |
| Gene ID number: |
6693 |
| Swiss Prot: |
P16150 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity), Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding, Is a counter-receptor for SN/Siglec-1 (By similarity), Plays a role in the physicochemical properties of the T-cell surface and in lectin binding, Presents carbohydrate ligands to selectins, One of the major glycoproteins of thymocytes and T lymphocytes |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CD43, GALGP, GPL115, Galactoglycoprotein, Leukocyte sialoglycoprotein, Leukosialin, SPN, Sialophorin, LSN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CD43/SPN |
| Short name: |
CD43/SPN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CD43/sialophorin (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD43 and GALGP and GPL115 and LSN, Extracellular, SPN and IDBG-24512 and ENSG00000197471 and 101929889, SPN and IDBG-639328 and ENSBTAG00000026326 and 614645, Spn and IDBG-210057 and ENSMUSG00000051457 and 20737, protein binding, this GO :0001562 and response to protozoan and biological process this GO :0001808 and negative regulation of type IV hypersensitivity and biological process this GO :0001931 and uropod and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005604 and basement membrane and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006955 and immune response and biological process this GO :0006968 and cellular defense response and biological process this GO :0007162 and negative regulation of cell adhesion and biological process this GO :0007163 and establishment or maintenance of cell polarity and biological process this GO :0007165 and signal transduction and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0031295 and T cell costimulation and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0042535 and positive regulation of tumor necrosis factor biosynthetic process and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0050688 and regulation of defense response to virus and biological process this GO :0050776 and regulation of immune response and biological process this GO :0050868 and negative regulation of T cell activation and biological process this GO :0050900 and leukocyte migration and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, 6693, sialophorin |
| Identity: |
11249 |
| Gene: |
SPN |
More about : SPN |
| Long gene name: |
sialophorin |
| Synonyms gene name: |
CD43) , leukosialin, sialophorin (gpL115 |
| Synonyms: |
LSN CD43 GPL115 |
| Synonyms name: |
leukosialin |
| Locus: |
16p11, 2 |
| Discovery year: |
1988-08-31 |
| GenBank acession: |
J04536 |
| Pubmed identfication: |
2784859 2521952 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000097765 |