| Long name: |
Biotin Conjugated, Apelin Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Apelin |
| Specificity: |
This is a highly specific antibody against Apelin |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Apelin |
| Gene ID number: |
8862 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Apelin and APJ are ubiquitously expressed in peripheral tissues, In the cardiovascular system several actions of Apelin have been described, The actions of apelin remain largely unknown: Apelin inhibits HIV-1 entry in cells coexpressing CD4 and APJ, a G protein-coupled orphan receptor which is an alternative coreceptor with CD4 for HIV-1, as well several regions within the central nervous system, by influencing AVP release and drinking behavior, including endothelium-dependent vasodilatation, more recent studies have also indicated a role for Apelin in the central control of body fluid homeostasis, the oral intake of Apelin in colostrum and breast milk could have a role in the modulation of the immune responses in neonates, vasoconstriction through direct action on smooth muscle and positive inotropism, with highest levels reported for heart and lungs, Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei and is an endogenous ligand for APJ |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
APEL, APEL_HUMAN, APJ endogenous ligand, Apelin 13, Apelin-13, Apelin13, Apln, XNPEP2, AGTRL1 ligand |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Apelin Conjugated |
| Short name: |
Conjugated, Apelin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Apelin (Antibody to) |
| Alternative technique: |
antibodies |