| Long name: |
ALEXA FLUOR 488 Conjugated, Notch 2 Polyclonal Antibody |
| Also known as: |
Anti-Notch 2 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Notch 2 |
| Specificity: |
This is a highly specific antibody against Notch 2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1570-1620/2471 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Notch2 |
| Gene ID Number: |
4853 |
| Swiss Prot: |
Q04721 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Affects the implementation of differentiation, In collaboration with RELA/p65 enhances NFATc1 promoter activity and positively regulates RANKL-induced osteoclast differentiation, Involved in bone remodeling and homeostasis, Jagged2 and Delta1 to regulate cell-fate determination, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus, proliferation and apoptotic programs (By similarity), Functions as a receptor for membrane-bound ligands Jagged1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
N2N |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Notch 2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Notch 2 |
| Short name: |
Notch 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Notch 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
31862 |
| Gene: |
NOTCH2NL |
More about : NOTCH2NL |
| Long gene name: |
notch 2 N-terminal like |
| Synonyms gene name: |
Notch homolog 2 (Drosophila) N-terminal like |
| Locus: |
1q21, 1 |
| Discovery year: |
2004-12-02 |
| Entrez gene record: |
388677 |
| Pubmed identfication: |
14673143 |
| RefSeq identity: |
NM_203458 |
| Havana BLAST/BLAT: |
OTTHUMG00000013754 |